The chapter thoroughly examines the transformative influence of the Internet of Things (IoT) on Supply Chain Management (SCM) by assessing its pivotal role across various sectors and its integration with key technologies. It outlines IoT's communication protocols and categorizes its applications into four types based on the application domain. It showcases IoT's contributions to smart agriculture, disaster management, autonomous vehicles, healthcare, smart homes, industrial automation, and logistics. The chapter emphasizes IoT's advancements in SCM, including transparency, inventory management, risk mitigation, and demand forecasting, facilitated by technologies such as RFID, cloud computing, and blockchain. It also addresses data privacy, security, and adoption barriers, advocating for training, cost-effectiveness, and awareness initiatives. Overall, it underscores the necessity of embracing IoT for SCM optimization while addressing its challenges to ensure a prosperous future.