This thesis is not only the result of the last five years of work, but yes was a consequence of cumulative learning, experiences, and collaborations, on both personal and professional levels. I remember a friend when I was 12 years old. He asked me what I would like to be in the future. At that time I had no idea and replied that I would like to be a successful person. He asked me -"are there many successful people in your family?" -I answered -"As far as I know, no". He said -"So, be the first one!". His words made me realize I had a long journey ahead. I am glad I have met many extraordinary people who guided me to be who I am now. So, I am thankful to all those wonderful people who were and still are part of my life. I thank God for guiding me and giving me strength and hope through all these years. I thank my family, my mom Odete, my brothers Ju and Gui for being supportive and giving words of strength. I thank all my school friends, who gave me the first words of motivation, and all the other colleagues from school and from university who made part of my academic growth. Special thanks go to my great friends from USP Bruno, Pedro, Leo, Dió, MLydia, and many other great friends from LABES, who I will never forget. I thank all my professors from primary and high school who helped me shape who I am. I thank the professors from my bachelor's, master's, and doctorate degrees, who showed me the tools for me to start learning by myself. I am deeply grateful to Prof. Elisa for all the "good tanoshimis". For believing in me and accepting to oriented me during this journey. For being a person who has brought many possibilities in my life. Thank you so much for the great moments shared and for the good vibes! I thank all professionals and friends from Fraunhofer, in special Dr.