Toxic effect of tetracycline exposure on growth, antioxidative and genetic indices of wheat (Triticum aestivum L.)

Xie, Xiulan; Zhou, Qixing; Lin, Daohui; Guo, Jianmian; Bao, Yongbo

doi:10.1007/s11356-010-0398-8

Cited by 108 publications

(48 citation statements)

References 41 publications

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“…In this study, the MDA contents were significantly higher in high erythromycin concentration treatments compared to the control, indicating that high erythromycin concentrations induced stronger peroxidation and caused more serious damage to the cell membrane. However, a slight increase in the MDA content was observed at low concentrations (<0.01 g L −1 ) of erythromycin, suggesting less oxidative stress on M. flos-aquae and possibly accounting for the lack of growth inhibition [43].…”

Section: Discussionmentioning

confidence: 92%

“…Liu et al [29] found that Florfenicol stimulated the growth of Skeletonema costatum at concentrations of 0.5, 1.0 and 2.0 mg L −1 and significantly inhibited growth at concentrations > 2.0 mg L −1 . Xie et al [43] showed that tetracycline at 0.5-10 mg L −1 stimulated seed germination, cell mitotic division, and growth of wheat seedlings; however, tetracycline at the high concentrations (10-300 mg L −1 ) significantly inhibited these parameters in a concentration-dependent manner. In our study, low concentrations of erythromycin promoted the growth of M. flos-aquae, possibly due to the promotion of certain enzymes involved in physiological and biochemical reactions at certain erythromycin concentrations.…”

Section: Discussionmentioning

confidence: 99%

“…Concurrently, the activity of CAT was significantly enhanced by erythromycin concentrations of 10 g L −1 or higher. The increased SOD activity may be attributed to the overproduction of superoxide, which is considered to be the central component of signal transduction, resulting in the activation of existing enzyme pools or the increased expression of genes that encode SOD [43,51,52]. The enhancement of CAT activity is considered to be an adaptive trait against the damage caused by oxidative stress [53].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae

Wan

Guo

Peng

et al. 2015

Journal of Hazardous Materials

176

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae

Wan

Guo

Peng

et al. 2015

Journal of Hazardous Materials

176

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“…However, changes in morphological parameters are a secondary effect of toxic action of xenobiotics. Phytotoxic effects of tetracycline include reduction of the length of wheat roots and stems, and a decrease of their mitotic index (Xie et al, 2011), also lucerne responds identically when exposed to oxytetracycline (Kong et al, 2007). In order to counteract the reduction in water content plants accumulate protective compounds (Yin et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Role of decarboxylases in the biosynthesis of biogenic amines of pea growing in soil contaminated with lomefloxacin

Baciak¹

2017

Appl Ecol Env Res

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Abstract.Lomefloxacin is an antibiotic used in human and animal medicine that is excreted to the environment, where it is taken up by plants. In the present study, we identified a new, universal parameter of lomefloxacin's toxicity to pea. We showed that activity of arginine decarboxylase and putrescine, which is synthetised in this pathway is a very good toxicity parameter, as confirmed by the calculated EC indices. The lomefloxacin toxicity resulted in a complete inactivation of ornithine decarboxylase and increase of activities of arginine decarboxylase, and S-adenosylmethionine decarboxylase. We propose that putrescine is not synthesised directly from ornithine. Instead, we suggest that the biosynthesis pathway proceeds from arginine to agmatine and is catalysed by arginine decarboxylase, which is followed by the formation of N-carbamoylputrescine with the participation of agmatine imniohydrolase. N-carbamoylputrescine amidohydrolase is involved in the synthesis of putrescine with Ncarbamoylputrescine. The activity of S-adenosylmethionine decarboxylase in the roots and stems increased almost 5-fold, arginine decarboxylase in the roots increased up to 18-fold, while in the stems it increased 6-fold, and ornithine decarboxylase in the roots and stems increased 3.5-fold. The highest biogenic amines content was found in seedlings growing in soil contaminated with 50 mg×kg -1 of soil lomefloxacin. We also recommend quantifying the activity of decarboxylases by measuring the secreted CO 2 volume with a multi-gas analyser equipped with an infrared detector. It is a simple, reliable, and cheap technique. Keywords: morphological parameters of plants, decarboxylases activity, toxicity, infrared detectorAbbreviations: Lomefloxacin -LOM; Effect concentration for the inhibition of growth rate at the level of x % (x = 10,

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“…Tetracycline antibiotics are the most frequently found in agricultural soils throughout the world, and the residual compounds result in a potential threat to both plants and soil organisms even at concentrations that are commonly detected in agricultural soils (Aga et al 2005;Thiele-Bruhn and Beck 2005;Sarmah et al 2006;Karcı and Balcıoğlu 2009;Goetsch et al 2012). A mass of investigation on the occurrence of antibiotic resistance genes (ARGs) was derived from the selection by antibiotics in recent years, indicating the contamination of natural environments or their antagonistic effects to soil microorganisms and a latent environmental threat besides the promoted genetic toxicity to plants in the soil (Xie et al 2011;Gao et al 2013;Zhang et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Toxicity of OTC to Ipomoea aquatica Forsk. and to microorganisms in a long-term sewage-irrigated farmland soil

Chen

et al. 2016

Environ Sci Pollut Res

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Water spinach (Ipomoea aquatic Forsk.) was selected to investigate the effects of oxytetracycline (OTC) on the toxicity of soil contaminated by long-term sewage irrigation. After acute toxicity test in petri dish at nine different OTC-spiked levels for 48 h, the germination rate was found to be generally inhibited in all treatments treated with OTC but the root elongation and activities of several antioxidant enzymes, superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) were either forward or backward stimulated to varying extent. During a 60-day sub-chronic toxicity test by means of a pot experiment, activities of SOD, POD and CAT in both the leaf and root tissue at 25 mg OTC per kg soil (dry weight) and in root tissue at 1 mg OTC per kg soil (dry weight) were significantly different than those in other treatments, which also indicated the higher sensitivity of the root. The foliar photosynthetic rate, stomatal conductance and transpiration rate were all gradually inhibited in spite of elevated water use efficiency under the pressure of the different OTC concentrations, which were highly significant different at 10 mg OTC per kg soil (dry weight). Indices of soil microbial diversity at 4 mg OTC kg −1 soil were significantly different from those of the control, indicating the potential adverse effects of OTC to soil microorganisms. The results suggest that the introduction of OTC could damage both plants and soil microorganisms, and during sub-chronic incubation, the sensitivity of different indices generally followed the order of root tissue antioxidant enzyme activities, soil microbial diversity indices, leaf photosynthesis-related index and leaf tissue enzyme antioxidant activities. In addition, the application of livestock and poultry manure containing pollutants like OTC in farmland soil, especially if the soil has been contaminated before, should be taken more seriously in the context of the current pursuit of increased agricultural production.

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Toxic effect of tetracycline exposure on growth, antioxidative and genetic indices of wheat (Triticum aestivum L.)

Abstract: Tetracycline may have potential physiological, biochemical, and genetic toxicity to plant cells, and chromosome aberration and MDA might be sensitive bioindicators for tetracycline contamination than the other plant characteristics.

Cited by 108 publications

References 41 publications

Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae

Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae

Role of decarboxylases in the biosynthesis of biogenic amines of pea growing in soil contaminated with lomefloxacin

Toxicity of OTC to Ipomoea aquatica Forsk. and to microorganisms in a long-term sewage-irrigated farmland soil

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