Toxic Effects of Mentha piperita Extract on Culex quinquefasciatus Larvae (Diptera: Culicidae)

Subahar, Rizal; Putr, Adib Kamil; Fatmawaty,; Sahar, Nurhuda; Winita, Rawina; Susanto, Lisawati; Yulhasri,; Lubis, Nadar Sukri; Mulyati, .; Firman, Nurhadi Eko

doi:10.3923/je.2021.19.28

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, alternative insecticides, natural products, are needed to combat insecticide-resistant mosquitoes. Previous studies reported that natural products have a wide variety of bioactive compounds such as alkaloids, flavonoids, phenol, and terpenoids [11][12][13] . These bioactive compounds can kill various stages of the mosquito such as egg, larval, pupal, and adult stages.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Curcuma longa rhizome extract and curcumin against laboratory-reared Aedes Aegypti (Diptera: Culicidae) larvae: Alterations of cell ultrastructure and immunoreactivity of octopamine and tyramine in the midgut

Subahar¹,

Felim²,

Aulia³

et al. 2022

Int. J. Mosq. Res.

Self Cite

View full text Add to dashboard Cite

Plant bioactive compounds, as an alternative insecticide, play an essential role in mosquito control. The purpose of this study was to evaluate the effect of Curcuma longa rhizome extract and curcumin against Aedes aegypti larvae, focusing on changes in the cell ultrastructure and immunoreactivity of octopamine (OA) and tyramine (TA) in the midgut. The larval bioassay was used following WHO protocols. Ae. Aegypti 3 rd -4 th instars larvae collected from the laboratory were exposed to both different concentrations of C. longa rhizome extract and curcumin. Ultrastructural changes in the midgut cells were tested by transmission electron microscope (TEM). OA and TA in the midgut were detected by the immunohistochemical method. At 24 h, curcumin killed 100% of Ae. Aegypti larvae at a concentration of 4 ppm. The LC50 values of curcumin and the rhizome extract were 1.522 and 4.074 ppm respectively. The curcumin caused ultrastructural changes in the larval midgut; damaged cells, epithelial cells microvilli, cell membranes, nucleus, mitochondria, and other cell organelles. Curcumin and the rhizome extract decreased the immunoreactivity of OA and TA in the larval midgut. Curcumin showed significant larvicidal activity against Ae. aegypti larvae mediated by damaged cells and decreased immunoreactivity of OA and TA in the midgut.

show abstract

Section: Introductionmentioning

confidence: 99%

“…A previous study reported that Mentha piperita leaf extract affected OA and TA immunoreactivity in the midgut larvae of Culex quinquefasciatus. [12] . Based on the previous study, the study was conducted to determine whether C. longa rhizome extract also affected OA and TA in the midgut larvae of Ae.…”

Section: Introductionmentioning

confidence: 99%