Toxic effects of nitrogenous compounds (ammonia, nitrite, and nitrate) on acute toxicity and antioxidant responses of juvenile olive flounder, Paralichthys olivaceus

Kim, Jun-Hwan; Kang, Yue Jai; Kim, Kwang Il; Kim, Su Kyoung; Kim, Jong-Hyun

doi:10.1016/j.etap.2019.02.001

Cited by 122 publications

(47 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The alteration of environmental conditions can cause toxicity and induce changes in growth rate, physiological functions, and antioxidant and immune responses (Kim et al, 2019;Morash and Alter, 2016). Ammonia exposure has an adverse effect on the growth performance of abalones by decreasing food consumption and increasing oxygen consumption (Cheng et al, 2004;Harris et al, 1998).…”

Section: Discussionmentioning

confidence: 99%

Toxic effects of ammonia on the survival, growth, and oxidative and immune responses in the Pacific abalone, Haliotis discus hannai

Park¹,

Yu²,

Choi³

et al. 2021

Fish Aquat Sci

View full text Add to dashboard Cite

The accumulation of ammonia, a consequence of intensive aquaculture activity, can damage cultured animals. We analyzed the survival rates, growth, antioxidant responses, and immune responses of abalones, Haliotis discus hannai (mean shell length 70.2 ± 4.9 mm; mean body weight 36.9 ± 3.6 g), biweekly for four weeks, to determine the accumulated concentrations of ammonia (0, 0.1, 0.2, 0.4, 0.8, and 1.6 mg/L). In our biweekly measurements, a survival rate of ≥ 95% was observed for all concentrations of ammonia. The specific growth rate (SGR) decreased at ≥ 0.8 mg/L (p < 0.05), but the daily increment in shell length (DISL) showed no significant change (p < 0.05). Regarding antioxidant responses, the superoxide dismutase (SOD) activity of the hepatopancreas was increased at ammonia concentrations over 0.8 and 0.2 mg/L (p < 0.05) at two and four weeks, respectively, and the SOD activity of the gills increased at concentrations over 0.4 and 1.6 mg/L (p < 0.05) at four weeks. The catalase (CAT) activity of the hepatopancreas and gills increased at ammonia concentrations > 0.8 mg/L (p < 0.05). Phenoloxidase (PO) activity increased at ammonia concentrations over 0.8 mg/L (p < 0.05), and Lysozyme (LZM) increased at concentrations over 0.8 and 0.4 mg/L (p < 0.05). Overall, our findings indicated that ammonia concentrations over 0.8 mg/L in seawater might damage the SGR, antioxidant responses, and immune responses in H. discus hannai. Our findings suggest the necessity of improvement or reinstallation for abalone aquaculture systems and can be used to assess the toxic effects of ammonia on H. hannai.

show abstract

Section: Discussionmentioning

confidence: 99%

Toxic effects of ammonia on the survival, growth, and oxidative and immune responses in the Pacific abalone, Haliotis discus hannai

Park¹,

Yu²,

Choi³

et al. 2021

Fish Aquat Sci

View full text Add to dashboard Cite

show abstract

“…The exposure to ammonia stimulates SOD and CAT activity (Hegazi et al 2010; Kim et al 2017a; Kim et al 2017b); however, in prolonged exposure, both activities decline, and oxidative lesions appear, and the effects of intoxication are accelerated (Yang et al 2010). Similarly, high levels of exposure to nitrite induce the generation of ROS in fish, and antioxidant enzymes are activated to reduce oxidative damage (Wang et al 2004; Vazquez et al 2009; Sun et al 2014; Kim et al 2019).…”

Section: Nitratementioning

confidence: 99%

“…Nitrate toxicity also induces oxidative stress by generating reactive oxygen and nitrogen species such as hydrogen peroxide, peroxynitrite and superoxide anion (Chen et al 2018). In Paralichthys olivaceus , the exposure to nitrate induced a significant increase in SOD and CAT activities, except for CAT activity in the kidney (Kim et al 2019). In summary, all compounds related to the metabolism of N present some degree of toxicity; thus, their elimination or reduction down to the tolerance levels is desirable.…”

Section: Nitratementioning

confidence: 99%

The nitrification process for nitrogen removal in biofloc system aquaculture

Robles‐Porchas

Gollas‐Galván

Martínez‐Porchas

et al. 2020

Reviews in Aquaculture

View full text Add to dashboard Cite

Aquaculture is an economic activity that faces the unavoidable problem of water quality detriment, which is mainly generated by the improper management of production ponds, including inadequate water circulation and aeration, accumulation of undigested food residues, excretion of metabolic by‐products by the cultivated organisms and other. In addition, the increase in suspended organic matter together with the presence and generation of nitrogen compounds can severely affect the physiology of the animal, leading to significant losses in production. Ammonia (NH3), nitrite (NO2) and nitrate (NO3) are toxic in different scales and environmental conditions; therefore, reducing their concentrations in the culture units has paramount relevance. In this regard, bioflocs are an efficient alternative to transform nitrogen compounds into a non‐toxic form, taking advantage of the capabilities of the microbial communities conforming them. Also, nitrogen can be harnessed and incorporated as organic nitrogen, making the biofloc a source of useful natural food for the cultivated organism. The substantial reduction in the rate of water exchange favoured by the biofloc technology (BFT) is a beneficial advantage for both the production systems and the environment, diminishing the risk of introducing pathogens into the pond in parallel with the improvement in the water quality of effluents. Ammonia oxidation is an advantage adding value to the BFT systems and is discussed in this review.

show abstract

“…Nitrite, a strong oxidant that is the intermediate product of the biological oxidation of ammonia to nitrate (Valencia-Castaneda et al, 2019), is one of the most common toxins in aquaculture water (da Silva et al, 2018). Exposure to nitrite decreases oxyhemoglobin levels in mammals, leading tissue hypoxemia and hypoxia (Cheng and Chen, 2002b;Kim et al, 2019). As the prosthetic group of the hemocyanin in crustacean blood is also a copper-containing compound, hemocyanin may behave similarly to hemoglobin; therefore, nitrite exposure in crustaceans might lead to hypoxia, cyanosis, or even death (Chen and Lee, 1997;Cheng and Chen, 2002a).…”

Section: Introductionmentioning

confidence: 99%

Construction of a High-Density Genetic Map and Identification of Quantitative Trait Loci for Nitrite Tolerance in the Pacific White Shrimp (Litopenaeus vannamei)

et al. 2020

View full text Add to dashboard Cite

Nitrite is a major environmental toxin in aquaculture systems that disrupts multiple physiological functions in aquatic animals. Although nitrite tolerance in shrimp is closely related to successful industrial production, few genetic studies of this trait are available. In this study, we constructed a high-density genetic map of Litopenaeus vannamei with 17,242 single nucleotide polymorphism markers spanning 6,828.06 centimorgans (cM), with an average distance of 0.4 cM between adjacent markers on 44 linkage groups (LGs). Using this genetic map, we identified two markers associated with nitrite tolerance. We then sequenced the transcriptomes of the most nitrite-tolerant and nitritesensitive individuals from each of four genetically distinct L. vannamei families (LV-I-4). We found 2,002, 1,983, 1,954, and 1,867 differentially expressed genes in families LV-1, LV-2, LV-3, and LV-4, respectively. By integrating QTL and transcriptomics analyses, we identified a candidate gene associated with nitrite tolerance. This gene was annotated as solute carrier family 26 member 6 (SLC26A6). RNA interference (RNAi) analysis demonstrated that SLC26A6 was critical for nitrite tolerance in L. vannamei. The present study increases our understanding of the molecular mechanisms underlying nitrite tolerance in shrimp and provides a basis for molecular-marker-assisted shrimp breeding.

show abstract

Toxic effects of nitrogenous compounds (ammonia, nitrite, and nitrate) on acute toxicity and antioxidant responses of juvenile olive flounder, Paralichthys olivaceus

Cited by 122 publications

References 36 publications

Toxic effects of ammonia on the survival, growth, and oxidative and immune responses in the Pacific abalone, Haliotis discus hannai

Toxic effects of ammonia on the survival, growth, and oxidative and immune responses in the Pacific abalone, Haliotis discus hannai

The nitrification process for nitrogen removal in biofloc system aquaculture

Construction of a High-Density Genetic Map and Identification of Quantitative Trait Loci for Nitrite Tolerance in the Pacific White Shrimp (Litopenaeus vannamei)

Contact Info

Product

Resources

About