Toxic effects of novel organophosphorus insecticide (RPR-V) on certain biochemical parameters of euryhaline fish, Oreochromis mossambicus

Rao, J. Venkateswara

doi:10.1016/j.pestbp.2006.01.008

Cited by 140 publications

(71 citation statements)

References 30 publications

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“…An excess secretion of mucous in fish is a non-specific response against toxicants, forming a barrier between the body and the toxic medium, so as to minimize its irritating effect, or to scavenge it through epidermal mucus. Similar observations were made by Rao 19 following RPR-V exposure to euryhaline fish, Oreochromis mossambicus.…”

Section: Behaviour Of Normal and Exposed Fishsupporting

confidence: 85%

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Chebbi¹,

David²

2010

ScienceAsia

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A static renewal bioassay was conducted to determine the acute toxicity (LC50) of commercial grade organophosphate insecticide, quinalphos (25% emulsified concentration) to common carp, Cyprinus carpio. The acute toxicity of quinalphos to carp fingerlings exposed for 96 h was found to be 7.5 µl/l. The fish were exposed to sublethal concentrations (0.1LC50 and 0.2LC50) for up to 15 days. Fish in toxic media exhibited irregular, erratic, and darting swimming movements, hyper excitability, and loss of equilibrium and sinking to the bottom. Caudal bending was the chief morphological alterations during the exposure tenures. The carp were found to be under stress but mortality was insignificant in both sublethal concentrations. Considerable variation in respiratory rate was observed in both sublethal concentrations. The observed alteration in respiratory rates may be a consequence of impaired oxidative metabolism and elevated physiological response by the fish against quinalphos stress. The impairments in fish respiratory physiology and behavioural response even under recovery tenures may be due to slow release of sequestered quinalphos from the storage tissues.

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Section: Behaviour Of Normal and Exposed Fishsupporting

confidence: 85%

Untitled

Chebbi¹,

David²

2010

ScienceAsia

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“…Haemorrhage in the primary and secondary gill lamellae, degeneration and necrosis of epithelial cells, distortion of the secondary lamellae, and disruption of epithelial cells from pillar cells were observed in gill tissues of Anabas testudineus (Santhakumar et al 2001) similar to the present study. Degenerative changes in gills, such as detachment and lifting of the epithelial linings from the surface of the gills, uncontrolled regeneration of the primary lamellae and secondary lamellae, hypertrophy, hyperplasia, necrosis of the epithelial cells, dilation of the blood sinuses of the secondary lamellae, lamellar aneurysm, haemorrhages etc., were noticed after exposure to sublethal concentrations of profenofos (Rao 2006). Coutinho and Gokhale (2000) found epithelial lifting in the gills of carp (C. carpio) and tilapia (O. mossambicus) exposed to the effluents of a wastewater treatment plant.…”

Section: Discussionmentioning

confidence: 99%

Bioaccumulation and ultrastructural alterations of gill and liver in Asian sea bass,Lates calcarifer(Bloch) in sublethal copper exposure

Paruruckumani¹,

Rajan²,

Ganapiriya³

et al. 2015

Aquat. Living Resour.

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-Bioaccumulation and ultrastructural alterations in gill and liver tissues of 3-month old Asian sea bass, Lates calcarifer, in response to copper were studied by transmission electron microscopy (TEM). Fishes were exposed to two sublethal concentrations of copper (6.83 ppm and 13.66 ppm) for a period of 28 days. Accumulation of copper were higher in the liver followed by gills. The damaging effects of the histoarchitecture of gill tissues in coper-exposed sea bass were hypertrophy and hyperplasia of epithelial cells, severe oedema, telangiectasia and secondary lamellar fusion. In addition extensive vasodilation with stretching and necrosis of pillar cells were also noted. The liver showed hydropic swelling of hepatocytes with nuclear pyknosis and chromatin condensation. Blood congestion in sinusoids and accumulations of lipid droplets in the hepatocytes at higher concentrations were observed.

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“…Agricultural pesticides used against pests, undesirable herbs and agricultural diseases have been found to have adverse effects on the environment (Sarikaya & Yilmaz 2003). Environmental toxicology studies have confirmed that pesticides affect non-target species in the environment because these substances are not fully selective (Rao 2006). Pesticides are applied to crops in large amounts, only a small portion of which reaches the target.…”

Section: Introductionmentioning

confidence: 99%

Effects of the 2,4-D herbicide on gills epithelia and liver of the fish Poecilia vivipara

Vigário

Sabóia‐Morais

2014

Pesq. Vet. Bras.

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Pesq. Vet. Bras. 34(6):523-528, junho 2014 523 RESUMO.-[Efeitos do herbicida 2,4-D no epitélio das brânquias e no fígado do peixe Poecilia vivípara.] A toxicidade aguda do herbicida 2,4-D foi investigada através dos efeitos no peixe Poecilia vivípara (Bloch et Schneider, 1801). Grupos de peixes foram expostos ao herbicida nas concentrações de 10, 20 e 40ml por litro de água, durante 24 horas. As brânquias e o fígado foram estudados. A concentração letal média (CL50) do herbicida para a espécie em questão foi de 34,64ml/l. Foram realizadas colorações histoquímicas e coloração de Feulgen para identificar glicoconjugados e DNA, respectivamente, nos tecidos acima citados. Os métodos histoquímicos revelaram os tipos de glicoconjugados presentes nas células mucosas e nos grâ-nulos. Os quatro tipos de células mucosas apresentaram glicoconjugados neutros, ácidos, ou ambos em um mesmo tipo celular. Observou-se a presença crescente de sialomucinas do grupo controle até o grupo exposto a maior concentração de 2,4-D, sugerindo aumento da viscosidade do muco e, consequentemente, formação de placas que impedem as trocas gasosas e a osmorregulação. A fusão lamelar observada no grupo exposto a 40ml de 2,4-D sugere ser um mecanismo de defesa. Os hepatócitos apresentaram processo de vacuolização nos grupos 10 e 20ml/l. No grupo de 40ml/l, observou-se a presença de células de Ito, micronú-cleos e hepatócitos normais e outros com edema nuclear. Este estudo indica a importância da avaliação de riscos se- The 2,4-dichlorophenoxyacetic acid, usually named 2,4-D is one of the most widely used herbicides in the world. Acute toxicity of 2,4-D herbicide was investigated through its effects on guppies (Poecilia vivipara Bloch et Schneider 1801). Fish were exposed to the herbicide at concentrations of 10, 20 and 40μl per liter of water for 24 hours to determine its effects on gills and liver epithelia. The estimated LC50 was 34.64μl of 2,4-D per liter of water. Histochemical analyses and Feulgen's reaction were conducted to detect glycoconjugates and DNA, respectively, in gills and liver epithelia. Histochemistry revealed qualitative variations of glycoconjugates present on mucous cells and granules. The four types of mucous cells contained neutral granules, acids, or both. Increasing amounts of syalomucins were observed from the control group to the group exposed to the highest concentration of 2,4-D, suggesting increased mucous viscosity and the formation of plaques that could inhibit gas exchange and osmoregulation. Lamellar fusion observed in the group exposed to 40μl of 2,4-D suggests a defense mechanism. Hepatocytes showed vacuolization in the 10 and 20μl/L groups. The 40 μl/L group showed normal hepatocytes as well as changed ones, many Ito cells, micronuclei, and nuclear swelling. These effects may be associated with toxicity or adaptative processes to cellular stress. The data from this study indicates the importance of assessing similar risks to aquatic species and suggests that Poecilia vivipara is an adequate biological mo...

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Toxic effects of novel organophosphorus insecticide (RPR-V) on certain biochemical parameters of euryhaline fish, Oreochromis mossambicus

Cited by 140 publications

References 30 publications

Untitled

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Bioaccumulation and ultrastructural alterations of gill and liver in Asian sea bass,Lates calcarifer(Bloch) in sublethal copper exposure

Effects of the 2,4-D herbicide on gills epithelia and liver of the fish Poecilia vivipara

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