Toxic effects of selected trace elements contained in make-ups on female university students in Nigeria

Eneh, Onyenekenwa Cyprian

doi:10.1007/s10661-021-09161-4

Cited by 5 publications

(2 citation statements)

References 26 publications

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“…Our results, on the contrary, suggest a positive association between kidney function and plasma thallium concentration. Notably, this finding is in line with previous studies in the general population, and among lead workers, which showed that higher urinary thallium levels were associated with higher kidney function [ 27 , 28 , 29 , 30 , 31 ]. Although these associations were statistically significant, their clinical relevance appears limited: less than 2% of the variation in kidney function could be explained by variations in thallium concentration.…”

Section: Discussionsupporting

confidence: 92%

“…Finally, we only assessed thallium levels in plasma. Several previous studies found that urinary thallium concentration showed similar associations with kidney function as the plasma concentration in our study [ 27 , 28 , 29 , 30 , 31 ]. Future studies on urinary thallium and thallium clearance may be useful for providing more insight on the effects of thallium on the kidney.…”

Section: Discussionsupporting

confidence: 87%

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Plasma Thallium Concentration, Kidney Function, Nephrotoxicity and Graft Failure in Kidney Transplant Recipients

Kremer

Riemersma

Groothof

et al. 2022

JCM

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The nephrotoxic effects of heavy metals have gained increasing scientific attention in the past years. Recent studies suggest that heavy metals, including cadmium, lead, and arsenic, are detrimental to kidney transplant recipients (KTR) even at circulating concentrations within the normal range, posing an increased risk for graft failure. Thallium is another highly toxic heavy metal, yet the potential consequences of the circulating thallium concentrations in KTR are unclear. We measured plasma thallium concentrations in 672 stable KTR enrolled in the prospective TransplantLines Food and Nutrition Biobank and Cohort Study using inductively coupled plasma mass spectrometry. In cross-sectional analyses, plasma thallium concentrations were positively associated with kidney function measures and hemoglobin. We observed no associations of thallium concentration with proteinuria or markers of tubular damage. In prospective analyses, we observed no association of plasma thallium with graft failure and mortality during a median follow-up of 5.4 [interquartile range: 4.8 to 6.1] years. In conclusion, in contrast with other heavy metals such as lead, cadmium, and arsenic, there is no evidence of tubular damage or thallium nephrotoxicity for the range of circulating thallium concentrations observed in this study. This is further evidenced by the absence of associations of plasma thallium with graft failure and mortality in KTR.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 87%

Plasma Thallium Concentration, Kidney Function, Nephrotoxicity and Graft Failure in Kidney Transplant Recipients

Kremer

Riemersma

Groothof

et al. 2022

JCM

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Heavy metals research in Nigeria: a review of studies and prioritization of research needs

Idowu

2022

Environ Sci Pollut Res

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Nigeria is experiencing continuous economic and industrial transformations, typical of many developing nations. In addition to its well-established oil industry, which is infamous for exuding various kinds of pollutants, there is increased mining operations, indiscriminate disposal and burning of wastes, illegal oil re nery, and terroristic insurgency, all poised to increase the levels of heavy metal contaminants in the Nigerian environment. A recent revelation indicates that about 2 million people in Southwestern Nigeria alone could potentially be poisoned by lead (Pb) and mercury (Hg), emanating from illegal mining operations. This further underscores the importance of investigations of toxic trace metal levels in the country. The current review of 136 research articles was conducted to provide an understanding of the scope of heavy metals research in Nigeria and to prioritise needed research. The review recognised that the scope of heavy metals studies has been wide, covering matrices such as cosmetics, human blood, hair, medicines, foods, beverages, water, air, soil and crude-oil. However, important toxic metals, especially mercury (Hg), arsenic (As) and antimony (Sb) are largely under-investigated. Also, there is a need for more studies to be conducted in the Northern part of the country. Furthermore, studies need to focus on marine environments rather than the freshwater ecosystems alone. Techniques such as the inductively coupled plasma -optical emission spectrometry (ICP-OES) and particle -induced X-ray emission (PIXE) analyses are herein recommended to bridge the data gap, and to overcome limitations in trace metals analyses in the Nigerian total environment.

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Beryllium contamination and its risk management in terrestrial and aquatic environmental settings

Bolan

Wijesekara

Tanveer

et al. 2023

Environmental Pollution

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Toxic effects of selected trace elements contained in make-ups on female university students in Nigeria

Cited by 5 publications

References 26 publications

Plasma Thallium Concentration, Kidney Function, Nephrotoxicity and Graft Failure in Kidney Transplant Recipients

Plasma Thallium Concentration, Kidney Function, Nephrotoxicity and Graft Failure in Kidney Transplant Recipients

Heavy metals research in Nigeria: a review of studies and prioritization of research needs

Beryllium contamination and its risk management in terrestrial and aquatic environmental settings

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