Toxic effects of tin compounds on microorganisms

Cooney, J. J.; Wuertz, Stefan

doi:10.1007/bf01569539

Cited by 140 publications

(103 citation statements)

References 192 publications

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“…Recently, Xiao and Kisaalita have found that pyoverdines bind and oxidize Fe 2ϩ to Fe 3ϩ (38). The Sn-C bond can be polarized in either direction, so it can be attacked by nucleophilic and electrophilic reagents (9). Interestingly, Martin and Walton have reported that the tin-phenyl cleavage of DPT occurs with the coordination and nucleophilic attack of a chelating agent, such as 8-hydroxy quinoline in dimethyl sulfoxide (29).…”

Section: Resultsmentioning

confidence: 99%

“…Recent estimates suggested that the annual world production of organotins may be close to 50,000 tons (12). Trisubstituted organotin compounds have wide-ranging toxicological properties, and their biocidal uses (ϳ8,000 tons/year) have been reported to have detrimental environmental impacts (9,12). Of particular importance to the environment is the high toxicity of tributyl and triphenyl derivatives.…”

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confidence: 99%

“…The disappearance of organotin compounds from the environment is attributed to their biodegradation, photolysis, biological uptake, sedimentation, and flux (9,17,39). It has been reported that the mixed function oxygenase system in fish (13,26) and rat liver (24) metabolizes TBT with hydroxylation, whereas TPT is more resistant to the analogous monooxygenase attack even though it undergoes dephenylation in rats (24).…”

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confidence: 99%

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Degradation of Triphenyltin by a Fluorescent Pseudomonad

Inoue

Takimura

Fuse

et al. 2000

Appl Environ Microbiol

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Triphenyltin (TPT)-degrading bacteria were screened by a simple technique using a post-column highperformance liquid chromatography using 3,3,4,7-tetrahydroxyflavone as a post-column reagent for determination of TPT and its metabolite, diphenyltin (DPT). An isolated strain, strain CNR15, was identified as Pseudomonas chlororaphis on the basis of its morphological and biochemical features. The incubation of strain CNR15 in a medium containing glycerol, succinate, and 130 M TPT resulted in the rapid degradation of TPT and the accumulation of approximately 40 M DPT as the only metabolite after 48 h. The culture supernatants of strain CNR15, grown with or without TPT, exhibited a TPT degradation activity, whereas the resting cells were not capable of degrading TPT. TPT was stoichiometrically degraded to DPT by the solid-phase extract of the culture supernatant, and benzene was detected as another degradation product. We found that the TPT degradation was catalyzed by low-molecular-mass substances (approximately 1,000 Da) in the extract, termed the TPT-degrading factor. The other fluorescent pseudomonads, P. chlororaphis ATCC 9446, Pseudomonas fluorescens ATCC 13525, and Pseudomonas aeruginosa ATCC 15692, also showed TPT degradation activity similar to strain CNR15 in the solid-phase extracts of their culture supernatants. These results suggest that the extracellular low-molecular-mass substance that is universally produced by the fluorescent pseudomonad could function as a potent catalyst to cometabolite TPT in the environment.

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Section: Resultsmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Degradation of Triphenyltin by a Fluorescent Pseudomonad

Inoue

Takimura

Fuse

et al. 2000

Appl Environ Microbiol

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“…A number of bacterial processes on membrane functions can be inhibited by organotins, including effects on transduction, solute transport and retention and oxidation of substrates. The toxic effects on algae and fungi are little known 3 .…”

Section: Resultsmentioning

confidence: 99%

Activity of Tri-N-Butyl Tin maleate in carpets against Staphylococcus aureus and Aspergillus niger, verified through two methodologies: Inhibition Halo (HZ) and Inhibition Surface (Print)

Uehara

Franzolin

Viani

et al. 2008

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe aim of the present study was to verify the activity of the Tri-N-Butyl Tin maleate compound against Staphylococcus aureus and Aspergillus niger, after its industrial application in 40 samples of carpets of different materials (polypropylene, polyester, polyamide and wool). The qualitative assays were performed through two methodologies: Inhibition Halo (HZ) and Inhibition of Surface (Print). The carpet with the product inhibited 100% of bacterial (Staphylococcus aureus) and fungi (Aspergillus niger) growth, under the conditions of this study. The microbial inhibition was higher in upper portion of carpets. The methodologies employed appear to be adequate to test the bactericide and fungicide activities of the Tri-N-Butyl Tin maleate. The print methodology confirmed the results obtained by the inhibition zone assay. Further studies using the same methodologies are needed to confirm our results.

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“…59 CRUZ et al (Dubey et al, 2006). In bacteria, the interference with biological membranes (Cooney and Wuertz, 1989;Cruz et al, 2012) and the inhibition of amino acid uptake and growth (Jude et al, 1996;Singh and Bragg, 1979) has been reported.…”

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confidence: 99%