Toxic Epidermal Necrolysis: A Case Report in Azal hospital, Sana'a, Yemen

Abstract

Toxic epidermal necrosis (TEN) is a life-threatening connective tissue disorder also known as Lyell's syndrome, characterized by erythema, and epidermal detachment, manifests as blisters, and raw skin patches. Adverse drug reactions are the most common risk factors. TEN is identical with Steven-Johnson's syndrome (SJS), differs from the latter in that greater area of the skin is involved. In this article, we report a case of a 20 years old male patient who presented with complaints of lethargy, red eyes and blisters after prescription of carbamazepine. Following this, the drug was taken off immediately. The treatment included the administration of fluids and appropriate antibiotics for treating the fluid-filled vesicles. The treatment regimen continued for three weeks and was stopped when the skin lesions were minimal and there was an improvement in the overall health of the patient.