“…To estimate the causal effect of exposure to lead through contaminated soil on cognitive difficulty, we use instrumental variable (IV) methods (e.g., Bowden and Turkington 1984, Angrist et al 1996, Greenland 2000, Angrist and Krueger 2001, Hernan and Robins 2006, Martens et al 2006). This approach tackles those two issues at the same time, and was used recently to study the effects of lead exposure on fertility (Clay et al 2018). Besides establishing a clear pathway of exposure, an instrumental variable quasi-experimentally induces a group of children to be exposed to lead in soil and another group to not face that exposure (or to at least experience less exposure).…”