Toxicidad corneal tras migración de Ozurdex® a cámara anterior

Bernal, Lucas Ribé; Estévez, Benito Vilas

doi:10.1016/j.oftal.2016.01.008

Cited by 9 publications

(3 citation statements)

References 6 publications

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“…Anterior chamber migration of a dexamethasone intravitreal implant has been reported in patients with aphakia,[56] anterior chamber IOL (ACIOL),[78] iris claw lens,[491011] scleral-fixated lens,[121314] and posterior chamber IOL (PCIOL). [1516] In majority of the cases, ruptured capsule has been reported as a primary risk factor for the migration of the implant into anterior chamber.…”

Section: Discussionmentioning

confidence: 99%

“…[1516] In majority of the cases, ruptured capsule has been reported as a primary risk factor for the migration of the implant into anterior chamber. [4567891013] Vitrectomized eyes[56910111216] are at increased risk of migration of the implant to anterior chamber when the other factors described above are present. Peripheral iridectomy, especially basal or inferior which facilitates free passage of aqueous from posterior chamber to anterior chamber, has been described as another risk factor for the passage of implant into anterior chamber.…”

Section: Discussionmentioning

confidence: 99%

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Anterior chamber migration of a sustained-release dexamethasone intravitreal implant: A case report and review of literature

et al. 2019

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The purpose of the study was to report a case of migration of a dexamethasone intravitreal implant (Ozurdex ® ) into anterior chamber and review the literature pertaining to the anterior chamber migration of implant. Clinical data were collected from a patient, in whom a dexamethasone intravitreal implant migrated to anterior chamber. A review of literature was conducted to analyze additional reports. A 59-year-old aphakic patient with recalcitrant cystoid macular edema due to chronic idiopathic uveitis was treated with intravitreal injection of dexamethasone implant. Migration of the implant into anterior chamber was noted after a month of injection. Since his cornea was clear and intraocular pressure was normal, he was managed conservatively. Sixteen such reports of migration of implant into anterior chamber was analyzed to look into the possible etiologies and outcome. Disruption of lens capsule, large basal iridectomy, and prior vitrectomy are the primary risk factors for migration of dexamethasone implant into the anterior chamber.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Anterior chamber migration of a sustained-release dexamethasone intravitreal implant: A case report and review of literature

et al. 2019

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“…Dexamethasone implants are used for treatment of persistent macular edema refractory to anti-vascular endothelial growth factor (anti-VEGF) injections. These implants have been reported to occasionally migrate into the anterior chamber and cause temporary or even permanent endothelial damage even after removal of the implant [78–80]. In strabismus-correcting surgeries, simultaneous resection of three rectus muscles, or even two in patients with compromised blood flow, may result in anterior segment ischemia [81].…”

Section: Procedural Causesmentioning

confidence: 99%

A Review of Corneal Endotheliitis and Endotheliopathy: Differential Diagnosis, Evaluation, and Treatment

et al. 2019

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The corneal endothelium plays an integral role in regulating corneal hydration and clarity. Endotheliitis, defined as inflammation of the corneal endothelium, may disrupt endothelial function and cause subsequent visual changes. Corneal endotheliitis is characterized by corneal edema, the presence of keratic precipitates, anterior chamber inflammation, and occasionally limbal injection, neovascularization, and co-existing or superimposed uveitis. The disorder is classified into four subgroups: linear, sectoral, disciform, and diffuse. Its etiology is extensive and, although commonly viral, may be medication-related, procedural, fungal, zoological, environmental, or systemic. Not all cases of endothelial dysfunction leading to corneal edema are inflammatory in nature. Therefore, it is imperative that practitioners consider a broad differential for patients presenting with possible endotheliitis, as well as familiarize themselves with appropriate diagnostic and therapeutic modalities.

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Dexamethasone

2017

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Toxicidad corneal tras migración de Ozurdex® a cámara anterior

Cited by 9 publications

References 6 publications

Anterior chamber migration of a sustained-release dexamethasone intravitreal implant: A case report and review of literature

Anterior chamber migration of a sustained-release dexamethasone intravitreal implant: A case report and review of literature

A Review of Corneal Endotheliitis and Endotheliopathy: Differential Diagnosis, Evaluation, and Treatment

Dexamethasone

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