Toxicity Analysis of Hybrid Nanodiamond/Fe3O4 Nanoparticles on Allium cepa L

Abstract

Background and Objective. The study of the toxicity of hybrid nanoparticles is necessary before they are synthesized in the laboratory and used in any particular applications. The toxic behaviour of nanoparticles can cause harm for the living species on the Earth. The production of biocompatible hybrid nanoparticles is important. Hence, this study is aimed at determining that nanodiamond/Fe3O4 hybrid nanoparticles were prepared and used for the toxicity analysis on Allium cepa L. Materials and Methods. The chemicals of hydrochloric acid, nitric acid, FeCl3.6H2O, FeCl2.4H2O, NaCl, and NaOH (Sigma-Aldrich chemicals, USA) were utilized in this study. A statistical analysis was performed on the results with a prevalence of p < 0.05 . Results. A novel ND/Fe3O4 nanocomposite material was successfully synthesized by the in-situ method and characterized by various characterization techniques. The analysis of X-ray diffraction indicated the formation of an ND/Fe3O4 nanocomposite with both participating phases. The saturation magnification of the ND/Fe3O4 nanocomposite is 13.2 emu/g, whereas for a pure Fe3O4 nanomaterial, it is 47 emu/g. The weight rates of ND and Fe3O4 existent in the nanocomposite are 28% and 72%, respectively. From the electrical conductivity analysis, ND/Fe3O4 exhibits conductivity in the order of 27 times more compared to ND. Conclusion. The result implies that the product ND/Fe3O4 has both magnetic and electrical properties. The biocompatibility of the synthesized ND/Fe3O4 material was studied based on the in-vitro method.

A Study of Hyaluronic Acid’s Theoretical Reactivity and of Magnetic Nanoparticles Capped with Hyaluronic Acid

“…The identification of chromosomal aberrations was performed based on the literature [ 92 , 93 , 94 , 95 ] and our previous experience [ 96 , 97 ]. The underlying mechanisms of HA-MNPs’ interaction with the cellular nucleus involve the suspension’s uptake at the level of rootlets, diffusion towards the cell cytoplasm, iron cations’ release from the nanoparticle surface, and their penetration into the cell nucleus, where a catalytic effect is supposed to occur.…”

Chemical structures, biological activities, and medicinal potentials of amine compounds detected from Aloe species

“…The amino acids of Aloe plants have been reported by many authors in both quantitative and qualitative analyses. Although there are a number of methods to detect amino acids, many of the amino acids (Table 3) detected in Aloe species were using an amino acid analyzer equipped with an HPLC and UV detector (Kim et al, 2013;Chandra Sekhar Singh et al, 2018). In addition to that, HPLC and 1 H NMR were used for the detection of amino acids in Aloe species (Hendrawati et al, 2019;Martínez-Sánchez et al, 2020).…”