Toxicity and Occupational Health Hazards of Coal Fly Ash

Tumane, Rajani; Pingle, Shubhangi K.; Jawade, Aruna; Randive, Kirtikumar

doi:10.1007/978-3-030-99495-2_14

Cited by 2 publications

(1 citation statement)

References 38 publications

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“…Проблема комбинированного влияния токсических факторов на организм работающих сохраняет актуальность поиска ранних диагностических и эффективных лечебно-профилактических мероприятий для работающих в условиях производства [5][6][7][8][9]. Доказаны влияния отдельных токсикантов, в частности свинца, на нервную, кроветворную, пищеварительную системы, проявляющиеся нарушениями эпигенетического статуса, окислительным повреждением ДНК, изменением количества ретикулоцитов, окислительным стрессом, нейроповеденческими изменениями, генным полиморфизом активности глутатионпероксидазы, параоксоназы и металлотионеина-4 и метаболизма кальция с минеральной плотностью костной ткани [10][11][12][13][14][15][16][17][18][19][20][21]. Выявлены опасные варианты комбинированной токсичности наночастиц оксида цинка и оксида меди.…”

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Assessment of Neurophysiological Parameters of the Nervous System in Non-Ferrous Foundry Workers

Bakhtereva,

Leiderman,

Plotko

et al. 2023

Health risk analysis

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A comprehensive assessment of the health status includes the functional exploration of the central and peripheral nervous systems. Results of the neurophysiological examination allow elaboration of effective personified therapeutic and preventive programs for the core personnel of non-ferrous metal industry. Our objective was to study functional disorders of the central and peripheral nervous systems in smelter operators for further development of risk-based rehabilitation programs for workers engaged in production of non-ferrous metals. Two cohorts of male workers were examined. The case cohort included 60 smelter operators of a large metallurgical plant situated in the Sverdlovsk Region and the control cohort consisted of 50 unexposed employees. The cohorts were matched by age and years of work experience. The mean age of smelter operators was 37.8 ± 7.9 years and their mean length of current employment was 4.1 ± 4.6 years, while the total length of work under hazardous occupational conditions was 7.1 ± 6.0 years. The case cohort included 39 operators of refinery boilers (mean age: 35.6 ± 7.2 years, mean length of employment: 4.2 ± 4.7 years) and 21 operators of the ore thermal furnace (mean age: 41.9 ± 7.6 years, mean length of current employment: 3.9 ± 4.4 years). All subjects underwent a neurocognitive examination (higher brain function testing), electroneuromyography, the somatosensory evoked response test, and electroencephalography. The results of examining the higher brain function enabled us to form the neurocognitive profile of the workers. We revealed signs of mild cognitive impairment in 30 % and a decrease in the cognitive reserve in 35 % of the cases. The diagnosed peripheral nervous system disorders included distal sensory polyneuropathy of the upper and lower extremities, carpal and cubital tunnel syndromes, cervical and lumbar radiculopathy. The comprehensive neurophysiological examination helps detect early changes in the central and peripheral nervous systems. The findings should be taken into account when developing personal medical rehabilitation programs.

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Assessment of Neurophysiological Parameters of the Nervous System in Non-Ferrous Foundry Workers

Bakhtereva,

Leiderman,

Plotko

et al. 2023

Health risk analysis

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Functional disorders of the peripheral nervous system in metallurgical workers

Bakhtereva,

Leiderman,

Riabkova

2023

Hygiene and Sanitation

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Introduction. Early detection of functional changes in the nervous system makes it possible to clarify the etiopathogenetic effect of a whole set of adverse industrial factors, form a group at risk of occupational diseases, and develop preventive programs for given the main structural targets. The purpose of the study was to identify characteristics of functional disorders of the peripheral nervous systems in metallurgists exposed to occupational hazards. Materials and methods. We examined two cohorts of workers: a control cohort of forty men unexposed to occupational risk factors and a case cohort of 60 male employees of a metallurgical plant situated in the Sverdlovsk Region. The cohorts were matched by age (mean: 38.8±7.6 years) and work experience (5.1±4.7 years). The mean duration of exposure to occupational hazards was 7.1±6.0 years. We included 38 cases in the program of in-depth neurophysiological examination that consisted of assessment of neurological status, electroneuromyography (ENMG). Results. 73.9 % of the cases had no complaints. Functional disorders of peripheral nerves were diagnosed as distal polyneuropathy of the upper and lower extremities (47.4 %), median neuropathy (42.1 %), ulnar neuropathy (23.7 %), and radiculopathies (9.6 %). Noteworthy is the presence of additional damages of the median nerve at the carpal tunnel in 55.6 % of the cases having signs of distal polyneuropathy. Conclusions. A comprehensive neurophysiological examination, not required by the current order for periodic medical examinations, helps to identify dysfunctions of the nervous system at their early stages. It is necessary to form high-risk groups of patients to monitor the development of work-related nervous diseases.

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Toxicity and Occupational Health Hazards of Coal Fly Ash

Cited by 2 publications

References 38 publications

Assessment of Neurophysiological Parameters of the Nervous System in Non-Ferrous Foundry Workers

Assessment of Neurophysiological Parameters of the Nervous System in Non-Ferrous Foundry Workers

Functional disorders of the peripheral nervous system in metallurgical workers

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