Toxicity Evaluation of 4-Chloro-2-Methylphenoxyacetic Acid by Microtox and Comparison with FETAX

4-Chloro-2-Methylphenoxyacetic Acid Containing Compounds. Genotoxicity Evaluation by Mutatox® Assay and Comparison with Acute (Microtox®) and Embryo (FETAX) Toxicities

“…The toxicity endpoint is the median effective concentration (EC50) for inhibition of Photobacterium phosphoreum luminescence. FETAX, with its three endpoints, mortality (LC50), teratogenicity (TC50) and growth inhibition (MCGI), is a reliable bioassay that makes use of Xenopus embryos (Dumont et al 1983;Bernardino et al 1996). FETAX results may be useful in comparison with Mutatox results as the processes which ensure the stability of genetic material are basic to enable organisms to proliferate in their environment.…”