Toxicity mechanism of engineered nanomaterials: Focus on mitochondria

Yao, Yongshuai; Zhang, Ting; Tang, Meng

doi:10.1016/j.envpol.2023.123231

Environmental Pollution

2024

DOI: 10.1016/j.envpol.2023.123231

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Toxicity mechanism of engineered nanomaterials: Focus on mitochondria

Yongshuai Yao,

Ting Zhang,

Meng Tang

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2024

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Cited by 4 publications

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Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

Cao,

Lv,

Wei

2024

Clinical & Translational Med

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BackgroundBreast cancer remains a global health challenge, necessitating innovative therapeutic approaches. Immunomodulation and immunotherapy have emerged as promising strategies for breast cancer treatment. Engineered exosomes are the sort of exosomes modified with surface decoration and internal therapeutic molecules. Through suitable modifications, engineered exosomes exhibit the capability to overcome the limitations associated with traditional therapeutic approaches. This ability opens up novel avenues for the development of more effective, personalized, and minimally invasive interventions.Main bodyIn this comprehensive review, we explore the molecular insights and therapeutic potential of engineered exosomes in breast cancer. We discuss the strategies employed for exosome engineering and delve into their molecular mechanisms in reshaping the immune microenvironment of breast cancer.ConclusionsBy elucidating the contribution of engineered exosomes to breast cancer immunomodulation, this review underscores the transformative potential of this emerging field for improving breast cancer therapy.Highlights Surface modification of exosomes can improve the targeting specificity. The engineered exosome‐loaded immunomodulatory cargo regulates the tumour immune microenvironment. Engineered exosomes are involved in the immune regulation of breast cancer.

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Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

Cao,

Lv,

Wei

2024

Clinical & Translational Med

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Navigating Neurotoxicity and Safety Assessment of Nanocarriers for Brain Delivery: Strategies and Insights

Teixeira,

Lopes,

Amaral

et al. 2024

Acta Biomaterialia

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Impact of polystyrene nanoplastics on apoptosis and inflammation in zebrafish larvae: Insights from reactive oxygen species perspective

Pei,

Chen,

et al. 2024

Science of The Total Environment

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Toxicity mechanism of engineered nanomaterials: Focus on mitochondria

Cited by 4 publications

References 131 publications

Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

Navigating Neurotoxicity and Safety Assessment of Nanocarriers for Brain Delivery: Strategies and Insights

Impact of polystyrene nanoplastics on apoptosis and inflammation in zebrafish larvae: Insights from reactive oxygen species perspective

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