Toxicity of Common and Hairy Vetch Seed for Poults and Chicks

Harper, J. A.; Arscott, G. H.

doi:10.3382/ps.0411968

Cited by 24 publications

(13 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This suggests that the accumulation of g-glutamyl-b-cyanoAla might have another physiological role in plant cells. Both b-cyano-Ala and g-glutamyl-b-cyano-Ala are known to be the chief neurotoxic principals of V. sativa seed (Harper and Arscott, 1962;Ressler, 1962;Ressler et al, 1963Ressler et al, , 1969. Similarly, b-cyano-Ala and g-glutamyl-b-cyano-Ala in Arabidopsis might act as defense molecules against predators.…”

Section: Isoform-dependent Differential Action Of Bsas As Csase and Cmentioning

confidence: 99%

Physiological Roles of the β-Substituted Alanine Synthase Gene Family in Arabidopsis

Watanabe

Kusano²,

Oikawa³

et al. 2007

Plant Physiology

160

164

View full text Add to dashboard Cite

The b-substituted alanine (Ala) synthase (Bsas) family in the large superfamily of pyridoxal 5#-phosphate-dependent enzymes comprises cysteine (Cys) synthase (CSase) [O-acetyl-serine (thiol) lyase] and b-cyano-Ala synthase (CASase) in plants. Nine genomic sequences encode putative Bsas proteins in Arabidopsis thaliana. The physiological roles of these Bsas isoforms in vivo were investigated by the characterization of T-DNA insertion mutants. Analyses of gene expression, activities of CSase and CASase, and levels of Cys and glutathione in the bsas mutants indicated that cytosolic Bsas1;1, plastidic Bsas2;1, and mitochondrial Bsas2;2 play major roles in Cys biosynthesis. Cytosolic Bsas1;1 has the most dominant contribution both in leaf and root, and mitochondrial Bsas2;2 plays a significant role in root. Mitochondrial Bsas3;1 is a genuine CASase. Nontargeted metabolome analyses of knockout mutants were carried out by a combination of gas chromatography time-offlight mass spectrometry and capillary electrophoresis time-of-flight mass spectrometry. The level of g-glutamyl-b-cyano-Ala decreased in the mutant bsas3;1, indicating the crucial role of Bsas3;1 in b-cyano-Ala metabolism in vivo.

show abstract

Section: Isoform-dependent Differential Action Of Bsas As Csase and Cmentioning

confidence: 99%

Physiological Roles of the β-Substituted Alanine Synthase Gene Family in Arabidopsis

Watanabe

Kusano²,

Oikawa³

et al. 2007

Plant Physiology

160

164

View full text Add to dashboard Cite

show abstract

“…The destructive effects of these antinutritional factors on different organs of the body have been described elsewhere (3,9,10,16). However, to the knowledge of the authors, none of the previous studies investigated a direct or indirect effect of these factors on the immune response of a host.…”

Section: Resultsmentioning

confidence: 99%

Immune response to Newcastle disease virus in broilers: a useful model for the assessment of detoxification of ervil seeds

Barbour

Kallás²,

Farran³

2001

Rev. Sci. Tech. OIE

View full text Add to dashboard Cite

Throughout the centuries, many countries have produced seed crops that were adapted to their specific environment and were used as a source of protein in feed for animals or poultry (4, 20). However, following the development of basic analytical sciences in the 19th Century and further refinement of analytical techniques in the 20th Century, scientists recognised the presence of toxicosis in poultry species, due to the use of certain crops in feed (18). Ervil (Vicia ervilia) seeds have been produced for centuries in the Mediterranean region, as a source of protein for cattle and poultry (4). The models used to assess the toxic effects of

show abstract

“…Such compounds are toxic to monogastric species, such as chickens or pigs, but have no obvious effect upon ruminant species, including beef cattle (Valentine and Bartsch, 1996). The proportion (w/w) of common vetch seed within feeds that can be safely consumed without deleterious effects is 10% for piglets and 20% for adult pigs and for chickens about 40% (Harper and Arscott, 1962;Rathjen, 1997). In addition to the main toxin GBCA, other anti-nutritional compounds were also found in common vetch included vicianine, vicine, convicine, and tannins (Ritthausen and Kreusler, 1870;Rathjen, 1997).…”

Section: Common Vetch Seeds: Important Nutritional Attributesmentioning

confidence: 99%

Common Vetch: A Drought Tolerant, High Protein Neglected Leguminous Crop With Potential as a Sustainable Food Source

et al. 2020

View full text Add to dashboard Cite

Global demand for protein is predicted to increase by 50% by 2050. To meet the increasing demand whilst ensuring sustainability, protein sources that generate low-greenhouse gas emissions are required, and protein-rich legume seeds have the potential to make a significant contribution. Legumes like common vetch (Vicia sativa) that grow in marginal cropping zones and are drought tolerant and resilient to changeable annual weather patterns, will be in high demand as the climate changes. In common vetch, the inability to eliminate the γ-glutamyl-β-cyano-alanine (GBCA) toxin present in the seed has hindered its utility as a human and animal food for many decades, leaving this highly resilient species an "orphan" legume. However, the availability of the vetch genome and transcriptome data together with the application of CRISPR-Cas genome editing technologies lay the foundations to eliminate the GBCA toxin constraint. In the near future, we anticipate that a zero-toxin vetch variety will become a significant contributor to global protein demand.

show abstract

Toxicity of Common and Hairy Vetch Seed for Poults and Chicks

Cited by 24 publications

References 6 publications

Physiological Roles of the β-Substituted Alanine Synthase Gene Family in Arabidopsis

Physiological Roles of the β-Substituted Alanine Synthase Gene Family in Arabidopsis

Immune response to Newcastle disease virus in broilers: a useful model for the assessment of detoxification of ervil seeds

Common Vetch: A Drought Tolerant, High Protein Neglected Leguminous Crop With Potential as a Sustainable Food Source

Contact Info

Product

Resources

About