Introduction: Although, used of molluscicides to control the intermediate host of schistosomes is the best method of choice to control the spread of the snail fever among the people, synthetic molluscicides widely used are cost effective, not available and toxic to the aquatic lives and people that are completely or partially dependents on rivers or lakes water for their everyday supplement.
Aim: this research was aimed at investigation and comparison for the molluscicidal efficacy for S. occidentalis and M. oleifera leaves extracts against B. globosus (intermediate host of Schistosoma haematobium).
Methodology: Each of the plant was grinded into powder and purified through column using different solvents, B. globosus snails were collected from Shagari and Goronyo dams; we identified the animal using chart initially, later on the animals were confirmed as B. globosus by malacologist from Ahmadu Bello University Zaria, Nigeria; the Molluscicidal efficacy of the plants was tested against B. globosus and compared according to world health organization guidelines; mortality was calculated using Abbort’s formula and analysis of variance (ANOVA) was used to determine if there is significant different between the mean mortality at P<0.05; qualitative Phytochemical analysis was conducted to determine the chemicals presence in each plant and their combination.
Results: Present study reviled that fractions of the leaves combination showed significantly higher mortality of B. globosus in the present study followed by Fractions of S. occidentalis then that of M. oleifera. For the plants combination, extracts purified using methanol are highly toxic followed by fractions purified using hexane, then ethyl acetate fractions and least Molluscicidal potential was recorded in the fractions obtained using ethanol. S. occidentalis fractions of hexane were highly toxic followed by fractions of methanol, then fractions of ethyl acetate and least mortality was recorded from the fractions of ethanol. Similarly, for the M. oleifera, it was observed that, fractions of Methanol were highly toxic followed by hexane fractions then ethanol fractions and least mortality was observed in the fractions of ethyl acetate.
Conclusion: Column purified fractions for the combination for two plants leaves were highly potent for the control of B. globosus followed by S. occidentalis then M. oleifera.