Toxicoioglcal rehabilitation off absinthium liqueur

Schaefer, Irving J.; Bindler, F.; Lugnier, A.

doi:10.1016/0378-4274(94)90413-8

Cited by 5 publications

(4 citation statements)

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“…In contrast, the concentrations found in the vintage absinthes (<10 mg L −1 )2–4 certainly lie in the determined thujone range and validate our calculation. That none of the vintage absinthes had a concentration higher than 10 mg L −1 may be explained by different preparation of the wormwood herb between the absinthe manufacture in the 19 th century and current studies about wormwood composition.…”

Section: Resultssupporting

confidence: 84%

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Behaviour of thujone during distillation and possible concentration ranges in pre‐ban absinthe

Lachenmeier¹,

Kuballa²

2007

J Sci Food Agric

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A discrepancy in the magnitude of thujone concentrations in distilled pre-ban absinthe has existed until now. Concentrations of 260 mg L −1 were derived at by theoretical calculations. Tests of authentic pre-ban absinthes and studies concerning absinthes produced according to historic recipes found concentrations below 10 mg L −1 . In this study, the behaviour of thujone during distillation was studied and a significant discrimination was determined (80% yield in water-cum-steam distillation). The thujone concentrations in distilled pre-ban absinthe were then calculated with regard to the composition of wormwood derived from a literature review. Due to the large deviations of oil content and thujone concentration of wormwood, a typical Absinthe Suisse de Pontarlier from Duplais' 1855 recipe might have contained between zero and a maximum of 76 mg L −1 of thujone, the average was calculated as 23 mg L −1 with a standard deviation of 21 mg L −1 . It was proven that the previous calculations overestimated the thujone content of distilled absinthe and the discrepancy was resolved as our new calculations are in good accord with the experimental findings.

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Section: Resultssupporting

confidence: 84%

“…One piece of evidence shows that absinthes produced according to historic recipes contained only relatively low concentrations of thujone (mean: 1.3 ± 1.6 mg L −1 , range: 0–4.3 mg L −1 ) 2. Concentrations below 10 mg L −1 were also found in a number of tests of vintage absinthes 2–4…”

Section: Introductionmentioning

confidence: 99%

Behaviour of thujone during distillation and possible concentration ranges in pre‐ban absinthe

Lachenmeier¹,

Kuballa²

2007

J Sci Food Agric

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“…In a non peer-reviewed magazine article, Ashcraft reports tests on pre-ban absinthes conducted by T. Breaux, who found thujone amounts around 5 mg/l [ 97 ]. Schaefer et al found such low thujone concentrations (<0.01 mg/l) in a legal French absinthe dating from 1904 that the authors even proposed the "toxicological rehabilitation" of absinthe [ 98 ]. In a current study of the neuropsychiatric toxicity of absinthe by Luauté et al it was concluded that recent toxicological studies do not prove, any more than in Magnan's time, that the beverage itself was epileptogenic [ 99 ].…”

Section: Toxicological Rehabilitation Of Absinthementioning

confidence: 99%

Absinthism: a fictitious 19th century syndrome with present impact

Padosch

Lachenmeier

Kröner

2006

Subst Abuse Treat Prev Policy

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Absinthe, a bitter spirit containing wormwood (Artemisia absinthium L.), was banned at the beginning of the 20 th century as consequence of its supposed unique adverse effects. After nearly centurylong prohibition, absinthe has seen a resurgence after recent de-restriction in many European countries. This review provides information on the history of absinthe and one of its constituent, thujone. Medical and toxicological aspects experienced and discovered before the prohibition of absinthe are discussed in detail, along with their impact on the current situation. The only consistent conclusion that can be drawn from those 19 th century studies about absinthism is that wormwood oil but not absinthe is a potent agent to cause seizures. Neither can it be concluded that the beverage itself was epileptogenic nor that the so-called absinthism can exactly be distinguished as a distinct syndrome from chronic alcoholism.

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“…Schaefer u. Mitarb. [21] konnten nur so geringe Konzentrationen in einem legal her− gestellten französischen Absinth von 1904 nachweisen, dass sie bereits die ¹toxikologische Rehabilitation" von Absinth vor− schlugen. Bei eigenen Untersuchungen konnten 1,8 mg/L Thujon in einem Absinth von 1930 nachgewiesen werden [22].…”

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Absinth - Geschichte einer Thujon- oder Alkoholabhängigkeit?

Lachenmeier

2007

Fortschr Neurol Psychiatr

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The etiopathology of absinthe dependence was previously attributed to the effects of the wormwood constituent thujone. Current research proves otherwise. Foremost, it must be considered that the wormwood plant shows a very large variance in quantity of thujone (0 - 70 % in essential oil) dependent on chemo type and cultivation area. Thus, absinthe does not contain thujone in general. Experimental production of absinthes and analyses of vintage absinthes (1900 - 1930) consistently showed that they contained only relatively low concentrations of thujone below today's maximum limits. Scientific literature contains no proof that historic absinthes may have contained thujone in concentrations able to produce toxic effects. The current state of research considers absinthism to be a type of alcoholism with thujone playing none or only a secondary role.

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Toxicoioglcal rehabilitation off absinthium liqueur

Cited by 5 publications

References 0 publications

Behaviour of thujone during distillation and possible concentration ranges in pre‐ban absinthe

Behaviour of thujone during distillation and possible concentration ranges in pre‐ban absinthe

Absinthism: a fictitious 19th century syndrome with present impact

Absinth - Geschichte einer Thujon- oder Alkoholabhängigkeit?

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