1987
DOI: 10.1016/0048-3575(87)90078-2
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Toxicokinetics of the phototoxic allelochemical α-terthienyl in three herbivorous lepidoptera

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Cited by 48 publications
(25 citation statements)
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“…In continuous feeding experiments with CX-[~HIT, after 48 h of feeding, 84% of the radiolabel was found in the feces of the highly resistant insect, 0. nubilalis (LD50 698 pg/g), 67% in the moderately resistant insect, Heliothis virescens (LD50 474 pg/g), and 42% in the sensitive, M . sexta (LD,, 10 pg/g) (Iyengar et al, 1987). In a similar study, Hasspieler et al (1988) found that variations in the susceptibility amongst mosquito strains to a-T were due to differences in their ability to excrete the compound.…”
Section: Metabolism and Excretion Of Photooxidantsmentioning
confidence: 94%
“…In continuous feeding experiments with CX-[~HIT, after 48 h of feeding, 84% of the radiolabel was found in the feces of the highly resistant insect, 0. nubilalis (LD50 698 pg/g), 67% in the moderately resistant insect, Heliothis virescens (LD50 474 pg/g), and 42% in the sensitive, M . sexta (LD,, 10 pg/g) (Iyengar et al, 1987). In a similar study, Hasspieler et al (1988) found that variations in the susceptibility amongst mosquito strains to a-T were due to differences in their ability to excrete the compound.…”
Section: Metabolism and Excretion Of Photooxidantsmentioning
confidence: 94%
“…They are known for their antidepressant, anticonvulsant, anthelmintic, antispasmodic, antihistaminic, anesthetic, antipruritic, antitussive and analgesic action. Thiophene and its derivatives exhibit diverse biological properties, such as nemoticial, insecticidal, antibacterial, antifungal, antiviral and antioxidant activity [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15].…”
Section: Introductionmentioning
confidence: 99%
“…Alpha-terthienyl appears to be moderately toxic to mammals orally and dermally and is non-mutagenic, but it has the potential to photosensitize human skin at high doses (Arnason et al 1987). The environmental safety of a-T has been investigated in aquatic habitats at application rates that effectively control mosquito larvae.…”
mentioning
confidence: 99%
“…Derivatives and analogues have also been synthesized to investigate structure-activity relationships. Such studies could well lead to more efficient phototoxins in future (Arnason et al 1987). In fact, Roush et al (1991) recently reported analogs of a-T that are effective, light-activated miticides, one of which has been selected for field development.…”
mentioning
confidence: 99%
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