Toxicological profile foro-phenylphenol and its sodium salt

Toxicogenomic response of Pseudomonas aeruginosa to ortho-phenylphenol

“…Ortho-phenyphenol is used as a fungicide and as an antibacterial agent in a wide variety of settings. OPP is used as a hospital disinfectant, and as a fungicide and disinfectant for wood preservation, the treatment of vegetables and citrus fruits and textile production [ 11 , 12 ]. Results from toxicological studies indicate that OPP administered in diet, leads to the formation of tumors in the urinary bladder of rats [ 13 ].…”

Pharmacokinetics of 14C‐ortho‐phenylphenol following intravenous administration in pigs

“…The low volume of distribution in pigs (0.14 l kg −1 ) and humans (0.19 l kg −1 ) and low 14 C‐OPP remaining in the tissues of pigs (14% dose) suggests that the 14 C‐OPP remains mostly in the blood with little distribution to the tissues. Rats also have a low volume of distribution (0.08 l kg −1 ); however, high residual concentrations of OPP have been reported in the bladder (Stouten, ). This high residual bladder concentration was not present in pigs.…”

Miniaturized portable surface plasmon resonance immunosensor applicable for on-site detection of low-molecular-weight analytes

“…In the present work, we explore the possible application of SPR sensing in a smaller, inexpensive and portable format for detection of HBP, a carcinogenic and genotoxic compound used widely as a fungicide [26][27][28][29]. HBP is an important member of the polycyclic aromatic hydrocarbons and is highly carcinogenic for human and ecosystems [21,22].…”