Toxicology study of nanoclays adsorbed with the antimicrobial peptide nisin on Caenorhabditis elegans

Research of mechanisms of transformation and removal of antibiotics from wine by sorbents of different nature

“…Typically used to remove off-flavors in wort and wine, it is particularly effective for treating against moldy flavors, herbaceous flavors, and for decontaminating the mycotoxin ochratoxin A [7,8,9]. The high efficiency of the sorption of antibiotics by activated carbon was established, at a dosage of 1 g/dm 3 -80 % for nisin and 78% for natamycin. In our opinion, the high degree of removal of nisin and natamycin is associated with the high sorption capacity of activated carbon and its developed effective specific surface, capable of actively interacting with high molecular weight components of wine, including nisin and natamycin.…”

“…To establish the effective adsorption capacity of sorbents to remove antibiotics of microbial origin from wine, a model system was used. It was a mixture of dry table white wine of the Chardonnay variety and antibiotics nisin (E234) and natamycin (E235) at a mass concentration of 25 and 50 mg/dm 3 , respectively. The amount of applied antibiotics was determined based on the analysis of literature data.…”

“…Colloidal silicon dioxide (highly dispersed silica «Polysorb» with a particle size of up to 0.09 mm), activated carbon (vegetable coal with a specific surface area of about 1400 m 2 /g) and bentonite (in the form of a suspension of bentonite clays containing no colloidal fraction no less than 80%) were used as sorbents. The studied dosages of sorbents were 0.5; 1; 1.5 and 2.0 g/dm 3 .…”

“…Food quality control is an integral part of the overall food safety system [1][2][3][4][5][6]. The methods and approaches used in the study to disclose the mechanisms of sorption and removal of antibiotics of microbial origin from wines to increase consumer safety and control the quality of wine products are comparable to the studies of foreign scientists [1][2][3][4][5][6].…”

Halloysite nanotubes – the nano-bio interface

“…Numerous antibacterial compounds were loaded into the HNTs, such as antibiotics, [108][109][110][111][112][113] disinfectants, 114,115 essential oils, [116][117][118][119] and antimicrobial peptides. 120 For example, loading of the disinfectant chlorhexidine gluconate resulted in a sustained release rate, three times slower than the free compound. 114 Such preparations can be administered as pastes and ointments, or even directly sprayed onto surfaces as an aqueous suspension (3-5 wt% HNTs).…”