Toxocariasis Possibly Caused by Ingesting Raw Chicken

Nagakura, Kouichi; Tachibana, Hiroshi; Kaneda, Yoshimasa; Kato, Yuko

doi:10.1093/infdis/160.4.735

Cited by 89 publications

(58 citation statements)

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“…Infections caused by ingesting encapsulated larvae in raw or undercooked infected organs or muscle tissues from paratenic hosts, such as chicken, lamb, or rabbit, have been reported from adults in northeastern Asian countries, e.g., Japan or South Korea, albeit rarely ( Fig. 1) (20,(42)(43)(44)(45)(46)(47)(48)(49). However, successful infection is influenced by a number of exposure-and susceptibility-related factors, including cultural and socioeconomic factors, environmental, geographic, and host immunity, genetics, age, gender, nutrition, coinfection, and the behavior of human and definitive hosts (20,50,51).…”

Section: Risk Factorsmentioning

confidence: 99%

Cerebral Toxocariasis: Silent Progression to Neurodegenerative Disorders?

et al. 2015

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SUMMARY Toxocara canis and T. cati are highly prevalent nematode infections of the intestines of dogs and cats. In paratenic hosts, larvae do not mature in the intestine but instead migrate through the somatic tissues and organs of the body. The presence of these migrating larvae can contribute to pathology. Toxocara larvae can invade the brains of humans, and while case descriptions of cerebral toxocariasis are historically rare, improved diagnosis and greater awareness have contributed to increased detection. Despite this, cerebral or neurological toxocariasis (NT) remains a poorly understood phenomenon. Furthermore, our understanding of cognitive deficits due to toxocariasis in human populations remains particularly deficient. Recent data describe an enhanced expression of biomarkers associated with brain injury, such as GFAP, AβPP, transforming growth factor β1 (TGF-β1), NF-L, S100B, tTG, and p-tau, in mice receiving even low doses of Toxocara ova. Finally, this review outlines a hypothesis to explore the relationship between the presence of T. canis larvae in the brain and the progression of Alzheimer's disease (AD) due to enhanced AD-associated neurodegenerative biomarker expression.

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Section: Risk Factorsmentioning

confidence: 99%

Cerebral Toxocariasis: Silent Progression to Neurodegenerative Disorders?

et al. 2015

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“…Ingestion of raw livers of pigs, lambs, and chicken has been reported as route of human infections [9][10][11][12]. We attempted to establish a role of eating habit of raw animal livers other than cow livers in toxocariasis.…”

Section: Discussionmentioning

confidence: 99%

“…They again become encapsulated and remain alive for a certain period. Uncooked livers of cow [3,[6][7][8], pig [9], lamb [10], and chicken [11,12] have been reported as sources of human infections. However, epidemiologic data on the role of ingesting raw liver of animals in the transmission of T. canis from animals-to-humans is limited [8].…”

Section: Introductionmentioning

confidence: 99%

Toxocariasis and Ingestion of Raw Cow Liver in Patients with Eosinophilia

et al. 2008

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Ingestion of raw animal liver has been suggested as a possible mode of infection of human toxocariasis. We evaluated the relationship between toxocariasis and the ingestion of raw meat in patients with eosinophilia of unknown etiology. The study population consisted of 120 patients presenting with peripheral blood eosinophilia (> 500 cells/ l or > 10% of the white blood cell count). They were divided into 2 groups: 104 seropositive patients based on a Toxocara excretory-secretory IgG ELISA and 16 seronegative patients. While 25.0% of seronegative patients had a recent history of eating raw cow liver, 87.5% of seropositive patients had this history. Multivariate statistical analysis showed that a recent history of eating raw cow liver was related to an increased risk of toxocariasis. Collectively, it is proposed that raw cow liver is a significant infection source of toxocariasis in the patients with eosinophilia of unknown etiology.

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“…Rodents, chicken, sheep, pigs, and birds are also other paratenic hosts for larvae (2). The parasite completes its life cycle in dogs and foxes (T. canis) and cats (T. cati) (2)(3)(4). Human toxocariasis can cause some diseases.…”

Section: Introductionmentioning

confidence: 99%

A Rare Cause of Hypereosinophilia: A Case Report

Merdin

Ögür²,

Kolak³

et al. 2016

TurkiyeParazitolDerg

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Toxocariasis is a parasitic disease caused by the larval stage of Toxocara cati and T. canis, which live in the intestinal system of cats (T. cati) and dogs (T. canis). Infective eggs can enter the gastrointestinal system by the oral route via foods contaminated with feces of dogs or cats or via dirty contaminated hands. The larvae penetrate the small intestine and migrate to visceral organs by systemic circulation. Hypereosinophilia is a common finding in the tissue invasion of parasites. Serological methods are the principle diagnostic methods for toxocariasis. In this study, we reported a toxocariasis patient presented with hypereosinophilia, hepatomegaly, and intestinal involvement. Computed tomography showed diffuse thickening of the ileal bowel loop walls around the umbilicus. Endoscopic ultrasonography revealed an enlarged periduodenal lymph node. Symptoms improved with albendazole treatment with a subsequent flare. Keywords: Hypereosinophilia, toxocariasis, atypical zoonosis ÖZ Toksokariazis, kedi ve köpeklerin barsaklarında yaşayan Toxocara canis ve Toxocara cati'nin neden olduğu parazitik bir hastalıktır. Enfektif yumurtalar kedi-köpek dışkısıyla kontamine olmuş besinlerle veya iyi yıkanmamış kontamine ellerle oral yoldan gastointestinal sisteme girebilir. Barsaklardan penetre olan larvalar iç organlara yerleşebilirler. Parazitlerin dokuya invazyonu sonucu hipereozinofili sık görülen bir bulgudur. Serolojik testler toksokaryozis tanısı konulmasındaki temel tanı yöntemidir. Biz bu olguda hipereozinofili, hepatomegali, ve barsak tutulumu ile prezente olan bir toksokoriazis vakasını bildirdik. Bilgisayarlı tomografide göbek etrafındaki ileal barsak anslarında yaygın duvar kalınlaşması görüldü. Endoskopik ultrasonografide büyümüş periduodenal lenf nodu saptandı. Semptomlar albendazol tedavisi aile düzelirken takip eden bir alevlenme görüldü.

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Toxocariasis Possibly Caused by Ingesting Raw Chicken

Cited by 89 publications

References 0 publications

Cerebral Toxocariasis: Silent Progression to Neurodegenerative Disorders?

Cerebral Toxocariasis: Silent Progression to Neurodegenerative Disorders?

Toxocariasis and Ingestion of Raw Cow Liver in Patients with Eosinophilia

A Rare Cause of Hypereosinophilia: A Case Report

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