2020
DOI: 10.1016/j.exppara.2020.108006
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Toxoplasma gondii: Cytokine responses in mice reinfected with atypical strains

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Cited by 3 publications
(1 citation statement)
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“…Rego et al [ 34 ] showed that the virulence profile of T. gondii strains obtained from pigs in Brazil was related to the presence of a specific allelic combination of ROP18 and ROP5 (allele 4 for ROP18 and allele 3 for ROP5 ). Furthermore, virulent T. gondii strains with the same allelic combinations for these proteins were able to induce higher levels of inflammatory cytokines, such as IFN-γ, IL-12, IL-17, and TNF-α, during early infection in mice [ 85 ]. However, the allelic profile of ROP5 and ROP18 can change among strains considered to be avirulent or to have intermediate virulence in mice [ 86 ].…”
Section: Toxoplasma Gondii Non-archetypal Strains: Virulence...mentioning
confidence: 99%
“…Rego et al [ 34 ] showed that the virulence profile of T. gondii strains obtained from pigs in Brazil was related to the presence of a specific allelic combination of ROP18 and ROP5 (allele 4 for ROP18 and allele 3 for ROP5 ). Furthermore, virulent T. gondii strains with the same allelic combinations for these proteins were able to induce higher levels of inflammatory cytokines, such as IFN-γ, IL-12, IL-17, and TNF-α, during early infection in mice [ 85 ]. However, the allelic profile of ROP5 and ROP18 can change among strains considered to be avirulent or to have intermediate virulence in mice [ 86 ].…”
Section: Toxoplasma Gondii Non-archetypal Strains: Virulence...mentioning
confidence: 99%