Toxoplasma gondii exposure in Brazilian indigenous populations, their dogs, environment, and healthcare professionals

Doline, Fernando Rodrigo; Santos, João Henrique Farinhas dos; Biondo, Leandro Meneguelli; Oliveira, Pollyanne Raysa Fernandes de; Rodrigues, Nássarah Jabur Lot; Patrício, Karina Pavão; Mota, Rinaldo Aparecido; Langoni, Hélio; Pettan-Brewer, Christina; Giuffrida, Rogério; Santarém, Vamilton Álvares; Castro, Wagner Antônio Chiba de; Santos, Andrea Pires dos; Kmetiuk, Louise Bach; Biondo, Alexander Welker

doi:10.1016/j.onehlt.2023.100567

Cited by 6 publications

(2 citation statements)

References 45 publications

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“…Furthermore, despite the absence of seropositivity in individuals with AHD and the comparatively low seroprevalence in dogs in the present study, B. PLOS NEGLECTED TROPICAL DISEASES canis outbreaks should be considered in such human populations due to the high burden and recurrent character of B. canis circulation in high-density dog populations and the constant introduction of susceptible animals. These findings in dogs highlight human vulnerability as a risk factor for brucellosis, as has been observed for other zoonotic diseases in homeless, indigenous, and quilombola communities [45][46][47][48]. In addition, negative results for individuals with AHD may indicate that B. canis has the lowest zoonotic potential in the genus Brucella [12,17].…”

Section: Discussionmentioning

confidence: 67%

One Health approach for Brucella canis: Serological and molecular detection in animal-hoarding individuals and their dogs

Schiavo,

Ribeiro,

de Almeida

et al. 2024

PLoS Negl Trop Dis

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Animal hoarding disorder (AHD) is classified as a psychiatric obsessive-compulsive condition characterized by animal accumulation and often accompanied by unsanitary conditions and animal cruelty. Although AHD may increase pathogen transmission and spread, particularly for zoonotic diseases, human and dog exposure in such cases has yet to be fully established. Accordingly, this study aimed to assess Brucella canis in 19 individuals with AHD (11 households) and their 264 dogs (21 households) in Curitiba, the eighth largest city in Brazil, with approximately 1.8 million habitants. Anti-B. canis antibodies were detected by the 2-mercaptoethanol microplate agglutination test (2ME-MAT) and by a commercial lateral flow immunoassay (LFIA), while molecular detection of previously positive seropositive samples was performed by conventional PCR. Although all the human samples were 2ME-MAT negative, 12/264 (4.5%, 95% Confidence Interval: 2.0–7.0%) dog samples were 2ME-MAT and LFIA positive, with 2ME-MAT titers ranging from 20 to 640. At least one dog in 4/21 (19.0%, 95% CI: 2.0–46.0%) households was seropositive. Despite the absence of seropositivity in individuals with AHD and the comparatively low seroprevalence in dogs, B. canis circulation and outbreaks should be considered in such human populations due to the high burden and recurrent character of B. canis exposure in high-density dog populations and the constant introduction of susceptible animals.

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Section: Discussionmentioning

confidence: 67%

One Health approach for Brucella canis: Serological and molecular detection in animal-hoarding individuals and their dogs

Schiavo,

Ribeiro,

de Almeida

et al. 2024

PLoS Negl Trop Dis

Self Cite

View full text Add to dashboard Cite

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“…The transmission routes include drinking water contaminated with oocysts, consumption of raw or undercooked meat of definitive or intermediate hosts containing tissue cysts of T. gondii, or via the transplacental route [10]. T. gondii causes toxoplasmosis in congenitally infected foetuses of homeothermic species worldwide [11,12]. The severity of fetal infection is associated with the gestational stage at the time of maternal infection, parasite burden, and genotypic characteristics [11].…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Practices Related to Dog-Associated Zoonoses in Ekiti State, Southwestern Nigeria

Omonijo,

Farayola

2024

PAJOLS

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Background: Human-dog contact has been associated with increased risks of zoonoses. However, dog owners’ knowledge and practice in preventing zoonoses transmission from dogs in Nigeria are limited. This study ex-plored dog owners’ knowledge and practices concerning zoonotic disease transmission. Methods: Semi-structured questionnaires were administered to households owning dogs to assess knowledge and practice of dog-contact-associated zoonoses (DCAZ). This cross-sectional study involved mothers, fathers, and young adults who closely interacted with dogs in households in Ado, Ido, Ikole, and Oye Local Government Areas (LGAs) of Ekiti State, Nigeria, from December 2021 to May 2022. The demographic characteristics of respondents were collected for statistical analysis using the statistical package for social sciences IBM-SPSS version 25.0. The relationship between respondents’ knowledge and demographic features was analysed using the Chi-square test of independence on SPSS. Results were considered significant at p < 0.05. Results: Overall, 200 dog owners participated in the study. The mean age of participants was 32.47 (±10.99). A significant difference (p<0.05) was observed in the number of dogs owned per household. The knowledge of dog contact-associated zoonoses (DCAZ) was estimated at 25.5% (51/200). Association between knowledge of DCAZ and sociodemographic factors showed that age, respondents’ identity, and level of education were signifi-cantly associated (p<0.05) with knowledge being highest among age group 41-50 and respondents with high lev-el of education. The practices of kissing dogs, walking barefooted, eating dog meat, and respondents’ preference for consumption of dog meat were observed to vary significantly among the study locations, with respondents from Ikole ranking higher at 54.0%, 50.0%, 14.0%, and 38.0% respectively (p<0.05). A significant difference was observed in the type of meat the respondents gave to their dogs (p<0.05). Overall, this study showed that 23.5% (47/200) of the respondents consumed dog meat, of which 68.1% (32/47) of the consumers showed a pref-erence for undercooked dog meat (p<0.05). Conclusion: This study showed the low level of knowledge regarding dog contact-associated zoonoses in Ekiti State and the need to intensify awareness of transmission routes and practices that facilitate disease transmission, utilising a One Health approach.

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Toxoplasma gondii infection in European brown hares (Lepus europaeus) in Brazil

Arias-Pacheco,

Perin,

de Oliveira Andrade

et al. 2024

Parasitol Res

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Toxoplasma gondii exposure in Brazilian indigenous populations, their dogs, environment, and healthcare professionals

Cited by 6 publications

References 45 publications

One Health approach for Brucella canis: Serological and molecular detection in animal-hoarding individuals and their dogs

One Health approach for Brucella canis: Serological and molecular detection in animal-hoarding individuals and their dogs

Knowledge and Practices Related to Dog-Associated Zoonoses in Ekiti State, Southwestern Nigeria

Toxoplasma gondii infection in European brown hares (Lepus europaeus) in Brazil

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