Toxoplasma gondii: Infection natural congenital in cattle and an experimental inoculation of gestating cows with oocysts

Costa, Gustavo Henrique Nogueira; Costa, Alvimar José da; Lopes, Welber Daniel Zanetti; Bresciani, Kátia Denise Saraiva; Santos, Thaís Rabelo dos; Esper, César Roberto; Santana, Áureo Evangelista

doi:10.1016/j.exppara.2010.08.005

Cited by 27 publications

(30 citation statements)

References 37 publications

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“…However, it is not mimic the natural route of infection in herbivorous such as ruminants. Differently, using sporulated oocysts (high dose, 10 5 ) to infect pregnant cows in mid gestation, COSTA et al (2011) did not observed either abortion or T. gondii from fetuses. Differently, from the present study, in another study (GARCIA et al, 2012) we did not observe statistical difference when prevalence of toxoplasmosis was compared between pregnant (23.9%) and non-Ciência Rural, v.42, n.6, jun, 2012. pregnant (28.6%) cows, however, this study used Bos indicus beef cows, and herein we used B. taurus dairy cows.…”

Section: Resultsmentioning

confidence: 99%

“…The factors that confer this natural resistance are not yet known (ESTEBAN-REDONDO & INNES, 1997). COSTA et al (2011) studied pregnant cows and their fetuses from a slaughterhouse in Jaboticabal, Brazil. The authors showed a positivity of 18% for toxoplasmosis, however, just low titers of 64 were observed.…”

Section: Resultsmentioning

confidence: 99%

“…Usually, T. gondii does not produce clinic signals, but the primary infection during pregnancy in women and a few animal species may result in abortion, fetal abnormalities or perinatal death (COOK et al, 2000). Despite of isolation in cattle fetuses, T. gondii is not an important cause of abortion in cattle (DUBEY, 1983;DUBEY, 1986;CANADA et al, 2002;COSTA et al, 2011).…”

Section: Toxoplasma Gondii é Um Parasito Reconhecido Mundialmente Commentioning

confidence: 99%

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Serum occurrence of anti-Toxoplasma gondii antibodies in dairy cows slaughtered in an abattoir for human consume

Macedo

Barros

et al. 2012

Cienc. Rural

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Toxoplasma Gondii é Um Parasito Reconhecido Mundialmente Commentioning

confidence: 99%

See 1 more Smart Citation

Serum occurrence of anti-Toxoplasma gondii antibodies in dairy cows slaughtered in an abattoir for human consume

Macedo

Barros

et al. 2012

Cienc. Rural

View full text Add to dashboard Cite

show abstract

“…However, it is not mimic the natural route of infection. Differently, using sporulated oocysts (high dose, 10 5 ) to infect pregnant cows in mid gestation, Costa et al (2011) did not observed either abortion or T. gondii from fetuses.…”

Section: Discussionmentioning

confidence: 99%

“…Costa et al (2011) studied pregnant cows and their fetuses from a slaughterhouse in Jaboticabal, Brazil. The authors showed a positivity of 18% for toxoplasmosis, however, just low titers of 64 were observed.…”

Section: Discussionmentioning

confidence: 99%

Sero-occurrence of anti-Toxoplasma gondii antibodies and vertical transmission in slaughtered beef cows (Bos indicus)

et al. 2012

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Toxoplasma gondii is a protozoan parasite recognized as an important public health problem. The objective of the present study was to evaluate the occurrence of anti-T. gondii antibodies in pregnant and non pregnant zebus' breed beef cows (Bos indicus), their fetuses, killed at an abattoir in northern of Paraná state. In the present study 169 cows were evaluated, 92 pregnant (in different stages of gestation) and 77 non pregnant. Sero-occurrence of anti-T. gondii antibodies was performed by Indirect fluorescent antibody test (IFAT) considering positive animals with titers ≥ 50 for cows and ≥ 25 for fetuses. Blood (with EDTA) from pregnant cows and blood and tissue samples (brain, lung, heart, and liver) from their fetuses were collected and used for mouse bioassay. Antibodies against T. gondii were observed in 26.0% of cows and 2.5% of fetuses. There was no statistical difference when prevalence of toxoplasmosis was compared between pregnant (23.9%), and non-pregnant (28.6%) animals, and age of gestation (p > 0.59). However, the occurrence of anti-T.gondii antibodies increased with age of animals (p=0.004). Mouse bioassay showed three fetuses positives (3.2%), however, none T. gondii strain was isolated. The present study showed that transplacental transmission of T. gondii naturally occurs in zebu beef cows from Brazil, however, in low rate (5.4%). The anti-T. gondii antibodies occurrence increase with the age of animals, which could be related to the fact that main transmission in cattle T. gondii is horizontal. Key words: Toxoplasmosis, zebu, vertical transmission ResumoToxoplasma gondii é um protozoário reconhecido como um dos mais importantes parasitas em saúde pública. O objetivo do presente estudo foi avaliar a ocorrência de anticorpos contra T. gondii em vacas de corte zebuínas (Bos indicus) gestantes, e seus fetos, bem como, em vacas não gestantes abatidas em um matadouro no norte do Paraná. No presente estudo foram avaliadas 169 vacas, 92 prenhas (em diferentes fases de gestação) e 77 não prenhas. A ocorrência de anticorpos contra T. gondii foi realizada por meio da reação de imunofluorescência indireta (IFI) considerando animais positivos aqueles com títulos ≥ 50 para as vacas e ≥ 25 para os fetos. Sangue (EDTA) de vacas prenhas e amostras de sangue e tecidos (cérebro, pulmão, coração, e fígado) de seus fetos foram coletadas e utilizadas para o bioensaio em camundongos. Anticorpos contra T. gondii foram observados em 26,0% das vacas e em 2,5% dos fetos Não houve diferença quando a soropositividade de anticorpos foi comparado entre vacas gestantes (23,9%), e não gestantes (28,6%), bem como, a idade da gestação (p > 0,59). No entanto, a ocorrência de anticorpos aumentou com a idade dos animais (p = 0,004). O bioensaio mostrou três fetos positivos (3,2%), porém, nenhuma cepa foi isolada. O presente estudo mostrou que a transmissão transplacentária de T. gondii ocorre naturalmente em vacas de corte zebuínas do Brasil, no entanto, esta ocorrência foi baixa (5,4%). A maior ocorrência de anticorpos a...

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Observational longitudinal study on Toxoplasma gondii infection in fattening beef cattle: serology and associated haematological findings

Dini,

Jacinto,

Cavallini

et al. 2024

Parasitol Res

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Toxoplasmosis, caused by the protozoan parasite Toxoplasma gondii, is a globally distributed zoonotic infection with significant implications for human and animal health. This study investigated the prevalence of T. gondii infection in a population of beef cattle at three different stages of their productive lifespan and examined the impact of T. gondii serological status on blood parameters. A commercial beef fattening unit in Italy was the setting for this research, which involved a biosecurity assessment upon cattle arrival, blood sampling at three time points and Toxoplasma-specific serological testing using indirect fluorescent antibody tests (IFAT). Results revealed a dynamic pattern of T. gondii seropositivity in cattle, with an initial prevalence of 30.6% at arrival (T0) that increased to 44.6% at 14 days (T1) and then decreased slightly to 39.3% at slaughter after 5 months (T2). Interestingly, seroconversion was observed during the study, indicating ongoing infections, and antibody waning occurred in some animals. In terms of blood parameters, seropositive cattle exhibited significantly lower mean corpuscular volume (MCV) and a higher neutrophil–lymphocyte (N/L) ratio, suggesting an activation of the innate immune response. Furthermore, cattle with higher antibody titres displayed higher neutrophil counts. However, all blood parameters with a statistical significance were within the reference range. This study provides for the first time a longitudinal investigation on the serological status for T. gondii in naturally exposed beef cattle. These findings provide valuable insights into the clinico-pathological aspects of natural T. gondii exposure in cattle and underscore the importance of monitoring and managing T. gondii infection in livestock production systems.

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Toxoplasma gondii: Infection natural congenital in cattle and an experimental inoculation of gestating cows with oocysts

Cited by 27 publications

References 37 publications

Serum occurrence of anti-Toxoplasma gondii antibodies in dairy cows slaughtered in an abattoir for human consume

Serum occurrence of anti-Toxoplasma gondii antibodies in dairy cows slaughtered in an abattoir for human consume

Sero-occurrence of anti-Toxoplasma gondii antibodies and vertical transmission in slaughtered beef cows (Bos indicus)

Observational longitudinal study on Toxoplasma gondii infection in fattening beef cattle: serology and associated haematological findings

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