Toxoplasmosis in a Hawaiian Monk Seal (Monachus schauinslandi )

Honnold, Shelley P.; Braun, Robert; Scott, Dana; Sreekumar, C.; Dubey, J. P.

doi:10.1645/ge-469r

Cited by 63 publications

(48 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Southern sea otter is listed as a threatened species under the Endangered Species Act in the USA. Toxoplasma gondii can cause fatal illness in sea otters and other marine mammals (Kreuder et al, 2003;Conrad et al, 2005;Honnold et al, 2005;Thomas et al, 2007;Dubey, 2010;Gibson et al, 2011). Sea otters are presumed to acquire T. gondii infection from the contamination of marine waters with oocysts washed from land (Miller et al, 2008b).…”

Section: Marine Mammalsmentioning

confidence: 99%

“…Honnold et al (2005) described clinical toxoplasmosis in a Hawaiian monk seal; DNA extracted from the tissues of the seal was considered Type III based on SAG2 typing. We re-characterised this T. gondii DNA using 10 additional markers and it had a Type I allele at SAG1, GRA6 and c22-8, and a Type III allele at c29-2 and L358; there was no amplification at the remaining five loci.…”

Section: Marine Mammalsmentioning

confidence: 99%

See 1 more Smart Citation

Genetic characterisation of Toxoplasma gondii in wildlife from North America revealed widespread and high prevalence of the fourth clonal type

Dubey

Velmurugan

Rajendran

et al. 2011

International Journal for Parasitology

162

View full text Add to dashboard Cite

a b s t r a c tLittle is known of the genetic diversity of Toxoplasma gondii circulating in wildlife. In the present study wild animals, from the USA were examined for T. gondii infection. Tissues of naturally exposed animals were bioassayed in mice for isolation of viable parasites. Viable T. gondii was isolated from 31 animals including, to our knowledge for the first time, from a bald eagle (Haliaeetus leucocephalus), five gray wolves (Canis lupus), a woodrat (Neotoma micropus), and five Arctic foxes (Alopex lagopus). Additionally, 66 T. gondii isolates obtained previously, but not genetically characterised, were revived in mice. Toxoplasma gondii DNA isolated from these 97 samples (31 + 66) was characterised using 11 PCR-restriction fragment length polymorphism (RFLP) markers (SAG1, 5 0 -and 3 0 -SAG2, alt.SAG2, SAG3, BTUB, GRA6, c22-8, c29-2, L358, PK1 and Apico). A total of 95 isolates were successfully genotyped. In addition to clonal Types II, and III, 12 different genotypes were found. These genotype data were combined with 74 T. gondii isolates previously characterised from wildlife from North America and a composite data set of 169 isolates comprised 22 genotypes, including clonal Types II, III and 20 atypical genotypes. Phylogenetic network analysis showed limited diversity with dominance of a recently designated fourth clonal type (Type 12) in North America, followed by the Type II and III lineages. These three major lineages together accounted for 85% of strains in North America. The Type 12 lineage includes previously identified Type A and X strains from sea otters. This study revealed that the Type 12 lineage accounts for 46.7% (79/169) of isolates and is dominant in wildlife of North America. No clonal Type I strain was identified among these wildlife isolates. These results suggest that T. gondii strains in wildlife from North America have limited diversity, with the occurrence of only a few major clonal types. Ó

show abstract

Section: Marine Mammalsmentioning

confidence: 99%

Section: Marine Mammalsmentioning

confidence: 99%

Genetic characterisation of Toxoplasma gondii in wildlife from North America revealed widespread and high prevalence of the fourth clonal type

Dubey

Velmurugan

Rajendran

et al. 2011

International Journal for Parasitology

162

View full text Add to dashboard Cite

show abstract

“…Currently, feral cats occur in low densities in montane forests and subalpine areas of Maui (Simons 1983) and Hawai'i Island (Hu et al 2001) and are frequent predators of endangered Hawai'ian birds including colonial seabirds (Smith et al 2002), ground-nesting waterfowl (Banko 1992), and tree-nesting passerines (Hess et al 2004). Cats also carry Toxoplasma gondii, which has caused fatal toxoplasmosis in endangered Hawai'ian birds (Work et al 2000(Work et al , 2002 and Hawai'ian monk seals (Monachus schauinslandi) (Honnold et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Using population genetic tools to develop a control strategy for feral cats (Felis catus) in Hawai'i

et al. 2007

View full text Add to dashboard Cite

Abstract. Population genetics can provide information about the demographics and dynamics of invasive species that is beneficial for developing effective control strategies. We studied the population genetics of feral cats on Hawai'i Island by microsatellite analysis to evaluate genetic diversity and population structure, assess gene flow and connectivity among three populations, identify potential source populations, characterise population dynamics, and evaluate sex-biased dispersal. High genetic diversity, low structure, and high number of migrants per generation supported high gene flow that was not limited spatially. Migration rates revealed that most migration occurred out of West Mauna Kea. Effective population size estimates indicated increasing cat populations despite control efforts. Despite high gene flow, relatedness estimates declined significantly with increased geographic distance and Bayesian assignment tests revealed the presence of three population clusters. Genetic structure and relatedness estimates indicated male-biased dispersal, primarily from Mauna Kea, suggesting that this population should be targeted for control. However, recolonisation seems likely, given the great dispersal ability that may not be inhibited by barriers such as lava flows. Genetic monitoring will be necessary to assess the effectiveness of future control efforts. Management of other invasive species may benefit by employing these population genetic tools.

show abstract

“…Feral domestic cats (Felis catus) in Hawaii may carry and transmit feline immunodeficiency virus (FIV), feline leukemia virus (FeLV), and the coccidian protozoan Toxoplasma gondii. Feline immunodeficiency virus and FeLV have been evaluated as potential biological control agents in island ecosystems (Courchamp and Sugihara, 1999), and T. gondii is known to cause illness in several Hawaiian bird species (Work et al, 2000(Work et al, , 2002, the endangered Hawaiian monk seal (Monachus schauinslandi) (Honnold et al, 2005), and humans (Dubey and Beattie, 1988).…”

mentioning

confidence: 99%

Evidence of Feline Immunodeficiency Virus, Feline Leukemia Virus, and Toxoplasma gondii in Feral Cats on Mauna Kea, Hawaii

Danner

Goltz

Hess³

et al. 2007

Journal of Wildlife Diseases

View full text Add to dashboard Cite

Toxoplasmosis in a Hawaiian Monk Seal (Monachus schauinslandi )

Cited by 63 publications

References 11 publications

Genetic characterisation of Toxoplasma gondii in wildlife from North America revealed widespread and high prevalence of the fourth clonal type

Genetic characterisation of Toxoplasma gondii in wildlife from North America revealed widespread and high prevalence of the fourth clonal type

Using population genetic tools to develop a control strategy for feral cats (Felis catus) in Hawai'i

Evidence of Feline Immunodeficiency Virus, Feline Leukemia Virus, and Toxoplasma gondii in Feral Cats on Mauna Kea, Hawaii

Contact Info

Product

Resources

About