“…U-net has been used extensively in this regard for the segmentation of brain structures. Various U-net models have been applied on MR images for brain tumor diagnosis [18], [19], [59], [45], [81], [106], [107], [87], [108]- [111], [92], [112]- [119], [44], [120]. U-net has also been applied on brain tissue for investigation of neurological conditions [54], [101], [103], [121]- [124], analysis of white matter tissue [125]- [127], [89], fetal brain development [128]- [131], and stroke lesions [69], [132]- [136].…”