Tracheobronchopathia osteochondroplastica: an unusual cause of chronic cough

Abouda, Maher; Jomni, T.; Charfi, M R

doi:10.1093/qjmed/hcv166

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…Thirty-six patients were included, five of them being previously reported [ 7 – 9 ]. They were mean aged 65 ± 12 years (36 to 88), and 20 (56%) were smokers (Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

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Tracheobronchopathia osteochondroplastica: clinical, bronchoscopic, and comorbid features in a case series

et al. 2022

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Background Tracheobronchopathia osteochondroplastica (TO) is a rare condition of unknown etiology. TO is characterized by submucosal nodules, with or without calcifications, protruding in the anterolateral walls of the trachea and proximal bronchi. The objective of this study was to describe TO features and associated comorbidities in a series of patients. Methods Patients suffering from TO were retrospectively included by investigators from the Groupe d’Endoscopie Thoracique et Interventionnelle Francophone (GETIF). Demographic, clinical, comorbidities, bronchoscopic, functional, and radiological characteristics, and outcomes were recorded and analyzed. Results Thirty-six patients were included (69% male with a mean of 65 ± 12 years). Chronic symptoms were described by 81% of patients including cough (74%) and dyspnea on exertion (74%). TO was associated with COPD in 19% of the cases and gastroesophageal reflux disease in 6%. A mild to severe airflow obstruction was present in 55% of the cases. CT scan showed tracheal submucosal nodules in 93% of patients and tracheal stenosis in 17%. Bronchoscopy identified TO lesions in the trachea in 65% of the cases, and 66% of them were scattered. A bronchoscopic reevaluation was performed in 7 cases, 9 ± 14 months [1–56] after initial diagnosis, and showed the stability of lesions in all cases. Three patients underwent interventional bronchoscopic treatment. Conclusion The diagnosis of TO relies on typical bronchoscopic findings and can be evoked on a CT scan. Histologic diagnosis can be useful in atypical cases for differential diagnosis. Given its low consequences in terms of symptoms, lung functions, and evolution, no treatment is usually required.

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“…Thirty-six patients were included, five of them being previously reported [ 7 – 9 ]. They were mean aged 65 ± 12 years (36 to 88), and 20 (56%) were smokers (Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…Hospital, University of Tunis El-Manar, 2070 Tunis, TN, Tunisia. 7 Department of Pneumology and Respiratory Functional Exploration, University Hospital of Tours, Tours, France. 8 Otolaryngology Department, Grenoble Alpes University Hospital, Grenoble, France.…”

Section: Authors' Contributionsmentioning

confidence: 99%

Tracheobronchopathia osteochondroplastica: clinical, bronchoscopic, and comorbid features in a case series

et al. 2022

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Clinicopathological Features and Management Principles of Tracheobronchopathia Osteochondroplastica - A Scoping Review

Devaraja

Surendra

2023

Indian J Otolaryngol Head Neck Surg

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Tracheobronchopathia Osteochondroplastica—Clinical, Radiological, and Endoscopic Correlation: Case Series and Literature Review

García

Sangiovanni

Zúñiga-Restrepo

et al. 2020

Journal of Investigative Medicine High Impact Case Reports

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Tracheobronchopathia osteochondroplastica (TO) is a rare idiopathic and benign disease that is often underdiagnosed. TO is characterized by multiple submucosal cartilaginous and osseous tracheobronchial nodules that spare the posterior wall. It usually affects the elderly, developing when the person is around 60 years old without gender preference and has a reported incidence of 0.11%. TO can be symptomatic and should be considered in patients with chronic cough, dyspnea, and recurrent pulmonary infections. Diagnosis is usually incidental by computed tomography or bronchoscopy, the latter being the gold standard diagnostic test for TO. Many thoracic imagers are not well acquainted with TO; thus, these patients are often underdiagnosed or misdiagnosed. We came across 5 patients in our institution who were incidentally diagnosed with TO, inspiring us to review the available literature on this disease. A total of 33 patients diagnosed with TO between 2009 and 2019 were identified by our retrospective review. Clinical and imaging data were collected on these patients. We also included the clinical, radiological, and endoscopic data of our 5 cases. TO should be considered in patients with chronic cough, dyspnea, and recurrent pulmonary infections. Our experience is that both computed tomography and bronchoscopy can be used to make a reliable diagnosis. It is crucial for physicians, especially radiologists and pulmonologists, to be aware of the existence of TO in order to ensure proper diagnosis.

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Tracheobronchopathia osteochondroplastica: an unusual cause of chronic cough

Cited by 4 publications

References 6 publications

Tracheobronchopathia osteochondroplastica: clinical, bronchoscopic, and comorbid features in a case series

Tracheobronchopathia osteochondroplastica: clinical, bronchoscopic, and comorbid features in a case series

Clinicopathological Features and Management Principles of Tracheobronchopathia Osteochondroplastica - A Scoping Review

Tracheobronchopathia Osteochondroplastica—Clinical, Radiological, and Endoscopic Correlation: Case Series and Literature Review

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