Tracheo-innominate artery fistula (TIF) is a surgical emergency with high mortality rates. Reported incidence is 0.1%-1.0% after tracheostomy with peak incidence 3 days to 6 weeks post procedure. TIF is usually fatal once it bleeds. For the successful management of TIF, treatment should be initiated immediately with the special considerations kept in mind. We describe two cases of TIF, and its clinical characteristics are reviewed in accordance with relevant literature.Keywords: tracheo-innominate artery fistula (TIF), tracheostomy, high-lying innominate artery source of bleeding, we performed flexible bronchoscopy that showed no active bleeding distal to the cannula tip. However, bleeding occurred again inside the tracheal tube. With the cuff of the tube maintained in the maximum hyperinflated state and the tracheostomy wound digitally compressed, the patient was immediately transferred to the operating room for surgical hemostasis. Unfortunately, we had no time to perform a computed tomography (CT) scan for this patient because this was an emergency case. A review of the CT scan, which had been taken about a year before, suggested that the TIF was probably above the sternal notch (Fig. 1). Therefore, unlike in the standard procedure, herein we made a suprasternal incision. After identifying the trachea and the overriding innominate artery, we successfully encircled the artery proximally and distally to the trachea and found the fistula posterior to the high-lying innominate artery. We debrided the fistulous segment of the innominate artery and reconstructed the artery in end-to-end fashion. Finally, the fistula of the trachea was repaired by suturing and the sternocleidomastoid flap was positioned between the trachea and artery to provide a mechanical barrier (Fig. 2). After controlling the blood flow of the fistulous segment of the artery, intra-tracheal bleeding was not observed. The amount of intra-operative bleeding was about 300 mL, and the operative time was 93 min. The post-operative course was uneventful with no sign of rebleeding. However, according to the findings of the CT