Tracing the footprints: A case of chronic meningitis with unusual mononuclear cells in the cerebrospinal fluid

Acosta, Andrés; Antoon, James W.; Kempe, Megan; Ahmad, Saba; Groth, John V.; Vályi-Nagy, Tibor; David, Odile; Cabay, Robert J.

doi:10.1002/dc.23684

Cited by 5 publications

(6 citation statements)

References 8 publications

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“…infiltrative, and increased intracranial pressure-related etiologies. Table 1 shows the neuro-ophthalmic findings reported in other cases of MM (10)(11)(12)(13).…”

Section: Trainees' Cornermentioning

confidence: 99%

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Neuro-Ophthalmic Manifestations of Mollaret Meningitis

Park

Bindiganavile²,

Nakawah³

et al. 2021

Journal of Neuro-Ophthalmology

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Mollaret meningitis (MM) refers to benign recurrent aseptic meningitis usually following herpes simplex virus 2 (HSV-2) infection. Neuro-ophthalmic manifestations associated with MM are rarely reported. We present a case of recurrent HSV-2 meningitis with the neuro-ophthalmic presentation of papilledema and sixth nerve palsy. To our knowledge, this is the first such description in the English language ophthalmic literature.

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“…infiltrative, and increased intracranial pressure-related etiologies. Table 1 shows the neuro-ophthalmic findings reported in other cases of MM (10)(11)(12)(13).…”

Section: Trainees' Cornermentioning

confidence: 99%

“…Neuro-Ophthalmic Findings Barontini et al (10) Anisocoria, dilation of the ventricles on computed tomography head Acosta et al (11) Papilledema, elevated opening pressure on LP (.55 cm H 2 O) Matta et al (12) Sixth nerve palsy Gadhiya et al (13) Disc edema with normal opening pressure LP, lumbar puncture.…”

Section: Authorsmentioning

confidence: 99%

Neuro-Ophthalmic Manifestations of Mollaret Meningitis

Park

Bindiganavile²,

Nakawah³

et al. 2021

Journal of Neuro-Ophthalmology

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“…62 The diagnosis is mostly based on the presence of trophozoites and/or cysts in CSF and brain biopsy specimens. 76 These characteristic mononuclear cells are usually present during the acute phase of this disease, mainly in the first 24 hours and hence can be easily missed. 63 Because of their appearance they have been curiously called "phantom" or "footprint" cells ( Figure 7B).…”

Section: P a R Asi T Ic I Nf E Cti On Smentioning

confidence: 99%

“…Because of their appearance they have been curiously called "phantom" or "footprint" cells ( Figure 7B). 76 These characteristic mononuclear cells are usually present during the acute phase of this disease, mainly in the first 24 hours and hence can be easily missed.…”

Section: Ol La R Et' S Meningitismentioning

confidence: 99%

Cerebrospinal fluid cytology in nonmalignant aseptic meningeal disorders

Martínez‐Girón¹,

Pantanowitz

2017

Diagnostic Cytopathology

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Cerebrospinal fluid cytology examination is a common and reliable primary and/or complementary procedure for the diagnosis of central nervous system (CNS) disorders. This review provides an update of aseptic meningeal disorders that may be encountered in cytopathology practice. The article covers the cytological findings and helpful ancillary studies needed of nonmalignant aseptic CNS disorders such as viral, bacterial, fungal and parasitic infections, and other noninfectious diseases, such as Mollaret's meningitis (recurrent benign lymphocytic meningitis), Guillain-Barré syndrome, multiple Sclerosis, subarachnoid haemorrhage, and drug-induced disorders.

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“…Due to fragility of the nuclear and cytoplasmic membranes in vivo, 1 Mollaret cells are infrequently detected after 24 hours from symptom onset in recurrent benign lymphocytic meningitis attacks. 2 They are encountered in up to 90% of cases of recurrent benign lymphocytic meningitis, or "Mollaret meningitis," which is strongly linked to HSV-2 reactivation from latent virus in sacral sensory ganglia. 3 However, there are reports of Mollaret cells in meningitis secondary to other herpesviruses (eg, herpes simplex virus 1 (HSV-1), varicella zoster virus (VZV)) and West Nile Virus.…”

mentioning

confidence: 99%