Research indicates that music can influence human cognitive functions. Diverse musical settings can affect alertness, orientation, and executive control of attention in various populations. Exploring the relationship between designers with highly creative thinking and music environments can provide new research perspectives for the cognitive field. A total of 94 students, consisting of 61 design majors and 33 non-design majors, completed the Attention Network Test (ANT) on a computer under three test environments: cheerful music, melancholic music, and silence. The study results indicated that the alerting network effect between the design professional group and the control group was marginally significant. However, there were no significant differences between the groups in the orienting subsystem and the executive control subsystem. Within the design professional group, the attentional network data indicated that participants showed improved performance in alerting and orienting attention in a music-free environment compared to cheerful and melancholic music environments (pa = 0.028, po = 0.008). Nevertheless, executive control attention did not show significant differences across the music environments. In conclusion, existing research confirms that designers are more susceptible to distraction from external stimuli; thus, music-free environments assist them in concentrating.