Background: A complex process like the blood transfusion chain could benefit from modern technologies like RFID. RFID could for example play an important role in generating logistic and temperature data of blood products, which are important in assessing the quality of the logistic process of blood transfusions and the product itself. Objectives: The aim of this study is to evaluate whether location, time-stamp and temperature data generated in real-time by an active RFID system containing temperature sensors attached to Red Blood Cell products (RBCs), can be used to assess the compliance of the management of RBCs to 4intra-hospital European and Dutch guidelines prescribing logistic and temperature constraints in an academic hospital setting. Methods: A RFID infrastructure supported the tracking and tracing of 243 tagged RBCs in a clinical setting inside the hospital at the Blood Transfusion Laboratory (BTL), the Operating Room (OR) complex and the Intensive Care Unit (ICU) within the Academic Medical Center (AMC), a large academic hospital in Amsterdam, The Netherlands. The compliance of the management of 182 out of the 243 tagged RBCs could be assessed on their adherence to the following guidelines on intra-hospital storage, transport and distribution: (1) RBCs must be preserved within an environment with a temperature between 2°C and 6°C; (2) RBCs have to be transfused within 1 hour after they have left a validated cooling system; (3) RBCs that have reached a temperature above 10°C must not be restored or must be transfused within 24 hours, or else be destroyed; (4) Unused RBCs are to be returned to the blood transfusion laboratory within 24 hours after they left the transfusion laboratory. Results: In total 4 blood products (4 in 182 compliant; 2%) complied to all applicable guidelines. Fifteen blood products (15 in 182 not compliant to 1 out of several guidelines; 8%) were not compliant to one of the guidelines of either 2 or 3 relevant guidelines; Finally 148 blood products (in 182 not compliant to 2 guidelines; 81%) were not compliant to 2 out of 3 relevant guidelines.
Conclusions:The results point out the possibilities of using RFID technology to assess the quality of the blood transfusion chain itself inside a hospital setting in reference to intra-hospital guidelines concerning the storage, transport and distribution conditions of RBCs. This study shows the potentials of RFID in identifying potential bottlenecks in hospital organizations' processes by use of objective data which are to be tackled in process redesign efforts. The effect of these efforts can subsequently be evaluated by the use of RFID again. As such, RFID can play a significant role in optimization of the quality of the blood transfusion chain.