Mesoscale convective systems (MCSs) are crucial in shaping large‐scale tropical circulation and the hydrological cycle, particularly in Northwestern South America (NwSA), a region marked by complex terrain and significant MCS activity. Understanding MCSs in NwSA is vital due to their impact on precipitation patterns and potential for severe weather events. To enhance this understanding, the ATRACKCS algorithm was developed for tracking convective systems, utilizing precipitation and brightness temperature data sets. This research focuses on documenting the spatiotemporal variability of MCS occurrence, life cycle, and movement. Notably, MCS hotspots were identified to the west of the major orographic features in the region, with maximum occurrences at night, contrasting with the region's typical afternoon peak in land convection. MCS movement is also heavily influenced by topography, with higher velocities on the eastern (windward) side of the Andes compared to velocities on the western (leeward) side. MCSs generally move westward, driven by easterly winds, but this pattern is not consistent throughout the year or region. Northward movement is predominant to the west of the Andes, while southward movement is observed to the east. These seasonal and regional movement variations are linked to factors such as the intertropical convergence zone position, moisture availability, topography, and low‐level jets. This research underscores the complexity of MCSs in NwSA and emphasizes the need for detailed studies on the atmospheric environment shaping these systems. Additionally, it provides a robust 21‐year MCS database for NwSA and an advanced tracking tool for research in various geographic contexts and impact areas.