Tractography of the Spider Monkey (Ateles geoffroyi) Corpus Callosum Using Diffusion Tensor Magnetic Resonance Imaging

Abstract

The objective of this research was to describe the organization, connectivity and microstructure of the corpus callosum of the spider monkey (Ateles geoffroyi). Non-invasive magnetic resonance imaging and diffusion-tensor imaging were obtained from three subjects using a 3T Philips scanner. We hypothesized that the arrangement of fibers in spider monkeys would be similar to that observed in other non-human primates. A repeated measure (n = 3) of fractional anisotropy values was obtained of each subject and for each callosal subdivision. Measurements of the diffusion properties of corpus callosum fibers exhibited a similar pattern to those reported in the literature for humans and chimpanzees. No statistical difference was reached when comparing this parameter between the different CC regions (p = 0.066). The highest fractional anisotropy values corresponded to regions projecting from the corpus callosum to the posterior cortical association areas, premotor and supplementary motor cortices. The lowest fractional anisotropy corresponded to projections to motor and sensory cortical areas. Analyses indicated that approximately 57% of the fibers projects to the frontal cortex and 43% to the post-central cortex. While this study had a small sample size, the results provided important information concerning the organization of the corpus callosum in spider monkeys.

Precise digit use increases the expression of handedness in Colombian spider monkeys (Ateles fusciceps rufiventris)

“…Recent work in A. geoffroyi using diffusion-tensor imaging found that the structural fibers of the corpus callosum were similar to that of chimpanzees and humans, but differed from that of rhesus monkeys, Macaca mulatta [Platas-Neri et al, 2015]. To date, there have been no neuroimaging studies that have examined relationships between brain and behavior asymmetries in Ateles.…”

“…In addition to behavioral studies, advances in neuroimaging have identified links between brain structure and hand preferences measured by the TUBE task in capuchin monkeys and chimpanzees [e.g., Dadda et al, 2006;Hopkins & Cantalupo, 2004;Li et al, 2010;Phillips & Hopkins, 2007;Phillips & Sherwood, 2005]. Recent work in A. geoffroyi using diffusion-tensor imaging found that the structural fibers of the corpus callosum were similar to that of chimpanzees and humans, but differed from that of rhesus monkeys, Macaca mulatta [Platas-Neri et al, 2015]. To date, there have been no neuroimaging studies that have examined relationships between brain and behavior asymmetries in Ateles.…”

Brain Connectivity in Ateles geoffroyi: Resting-State Functional Magnetic Resonance Imaging of Working Memory and Executive Control

“…In order to identify resting-state networks in our subjects, MRI data were first preprocessed and then a grouped ICA was performed using the GIFT software (http://icatb.sourceforge.net/). A more detailed description of this analysis can be seen in previous reports [de Celis Alonso et al, 2014;Platas-Neri et al, 2015]. Batch preprocessing of images was carried out using the SPM12 software (http://www.fil.ion.ucl.ac.uk/spm).…”

“…ICA was used in the present research since functional connectivity networks are unknown in spider monkeys [Hampson et al, 2002;Beckmann et al, 2005;Damoiseaux et al, 2006]. Distinct networks with potential functional relevance have been identified in humans [Biswal et al, 1995;Raichle et al, 2001;Hampson et al, 2002;Greicius et al, 2003;Beckmann et al, 2005;Damoiseaux et al, 2006], and manifest in highly organized patterns of coherence across mammalian species [Rilling et al, 2007;Vincent et al, 2007;Pawela et al, 2008;Kojima et al, 2009;Cabral et al, 2011;Barks et al, 2015;Platas-Neri et al, 2015].…”

Functional MR imaging (BOLD and resting States). Clinical and research applications

“…In this project 12 , collaboration with the Instituo Nacional de Psiquiatría de México, tractography and diffusion measurements of the corpus callosum of monkeys were obtained. We hypothesized that the arrangement of fibers in spider monkeys would be similar to that observed in other non-human primates.…”