A B S T R A C TUnderstanding the spatial distributions of multiple ecosystem services (ESs), their associations, and their underlying socio-ecological contributing factors is critical for ES management. Using the city belt along the Yellow River in Ningxia, northwestern China, as a case study, this study quantified the spatial distribution of six ESs (food production, carbon sequestration, carbon storage, nutrient retention, sand fixation and recreational opportunity), analyzed the synergy and trade-off relations among them through correlation analysis, classified ES bundles through a self-organizing map method (SOM), explored the impacts of socio-ecological factors on the ESs through Ordinary Least Square regression (OLS) and Geo-detector analysis, delineated socio-ecological clusters using the SOM, and characterized the relationship between ES bundles and driver clusters through overlap analysis. The results suggest that spatial associations among ESs can be predicted by their driving mechanisms. Synergy relations existed among crop production, carbon sequestration, carbon storage and nutrient retention, and these were impacted by similar driving mechanisms. Synergy also existed between sand fixation and recreational opportunity, but significant differences existed in their driving mechanisms. Trade-off relations were shown between ESs in these two groups at the whole region scale. Three bundles were detected among the six ESs: bundle 1, characterized by recreational opportunity of high supply and other services of limited supply, was located in the transitional region between the central plain and the fringe mountains, and mainly driven by climate and proximity factors; bundle 2, characterized by high sand fixation, medium carbon storage and limited other services, was located in the northwestern and southern mountains and driven by climate and geography factors; bundle 3, characterized by high food production, carbon sequestration, carbon storage and nutrient retention of medium supply and other two services of limited supply, was located in the central plain and driven by vegetation coverage and proximity factors. Human activities can partly overcome the limitations of ecological conditions, thus specific strategies for different regions are proposed to maintain and improve ESs under global climate change.