In this research work, the author focuses on the analysis of the trade interests in foreign policy of the Global South.What indicates the importance and innovativeness of the research is the presentation of the new models of the foreign trade policy and trade interests of Global South. First of all, it must underline that in the new theoretical terms in the demand for trade policy very important is factor specificity. The low specificity of factors means that factor returns are equalized throughout a region's economy. Moreover, some factors are stuck in their present uses; therefore, factor returns are not equalized throughout a region's economy, but are industry specific. The main objective of the research task is to give a comprehensive analysis of the models of foreign trade policy, trade interests indicated by export orientation and import sensitivity, protectionistic pressures in different political system and different types of authoritarian regimes of Global South, the level of protectionistic pressures, the rise of qualitatively new politics in North-South relations like bilateral tendencies. It should be stressed that free trade in itself is not responsible for economic growth, but more significant are the determining macroeconomic stability and increasing investment of Global South.