Traditional and innovative echocardiographic parameters for the analysis of right ventricular performance in comparison with cardiac magnetic resonance

Focardi, Marta; Cameli, Matteo; Carbone, Salvatore Francesco; Massoni, Alberto; Vito, Raffaella De; Lisi, Matteo; Mondillo, Sergio

doi:10.1093/ehjci/jeu156

Cited by 222 publications

(165 citation statements)

References 19 publications

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“…Conventional easy-to-measure RV function parameters such as TAPSE and tricuspid annular systolic velocity (TASV) confirmed a good correlation with PASP in both the echocardiography and catheterized patient groups of the present study. This is also consistent with results of a recent study by Focardi et alcomparing both conventional (TAPSE,TASV, FAC) and novel (RV strain) parameters with CMR, albeit in non-SSc patients [17].…”

Section: Discussionsupporting

confidence: 92%

Contribution of Speckle Tracking to Estimation of Pulmonary Hypertension by Standard Doppler Echocardiography in Patients with Systemic Sclerosis and MCTD

Vymětal¹,

Hutyra²,

Smarzova³

et al. 2017

Rheumatology (Sunnyvale)

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Objectives: Development of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) represents one of the most serious complications. The study aimed at assessing right ventricular (RV) global longitudinal strain and its relation to pulmonary artery pressure.Methods: Echocardiography was performed in 74 patients of whom 60 had SSc and 14 had mixed connective tissue disease (MCTD). Besides routine left and right ventricle assessment and pulmonary pressure estimation by Doppler echocardiography, RV fractional area change (FAC) and 2D strain of the RV free wall were evaluated. At the same time, levels of N-terminal pro-brain natriuretic peptide (NT-proBNP), troponin T and auto-antibodies were measured and all patients had diffusing capacity of the lung for carbon monoxide (DLCO) determined. All patients with probable PAH underwent right heart catheterization.Results: Pulmonary hypertension was found to be unlikely in 59 patients (79.7%), possible in 10 patients (13.5%) and probable in 5 patients (6.7%). Significant associations were found between pulmonary artery systolic pressure (PASP) and RV free wall global longitudinal strain (r=0.292; p=0.023), between PASP and NT-proBNP (r=0.436; p=0.001) and between PASP and FAC (r=0.320; p=0.005). Pulmonary artery systolic pressure did not correlate with left ventricular systolic or diastolic function parameters in this cohort. Conclusion:Speckle tracking of the RV represents a useful additional tool in RV assessment in relation to PH in SSc and MCTD patients; right heart catheterization remains an essential method for PAH confirmation.

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Section: Discussionsupporting

confidence: 92%

Contribution of Speckle Tracking to Estimation of Pulmonary Hypertension by Standard Doppler Echocardiography in Patients with Systemic Sclerosis and MCTD

Vymětal¹,

Hutyra²,

Smarzova³

et al. 2017

Rheumatology (Sunnyvale)

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“…In a (partial) ARVD/C cohort, mean RV free wall peak strain showed the strongest correlation with MRI obtained RVEF compared to other conventional 2D systolic parameters [48]. Several studies suggest an important role of exercise in the pathogenesis of ARVD/C [49,50].…”

Section: Systolic Deformationmentioning

confidence: 84%

Current and future role of echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Mast

Teske²,

Doevendans³

2015

Cardiol J

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“…[16–18] On the other hand, limitations of TAPSE and S’ are acknowledged in consensus ASE guidelines [8], and these indices have been shown to yield limited sensitivity and predictive value in heart failure cohorts receiving ventricular assist devices and undergoing cardiac surgery. [19–22] Our study did not directly test echo indices in relation to outcomes, but instead to a CMR surrogate of RVEF which has itself been validated as a prognostic index.…”

Section: Discussionmentioning

confidence: 99%

Echocardiographic linear fractional shortening for quantification of right ventricular systolic function—A cardiac magnetic resonance validation study

et al. 2017

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Background Echocardiography (Echo)-based linear fractional shortening (FS) is widely used to assess left ventricular dysfunction (LVdys), but has not been systematically tested for right ventricular dysfunction (RVdys). Methods The population comprised LVdys patients with and without RVdys (EF<50%) on cardiac MRI (CMR): Echo included standard RV indices (fractional area change [FAC], TAPSE, S’ and FS in parasternal long axis (RV outflow tract [RVOT]) and apical 4-chamber views (width [RVWD], length [RVLG]). Results 168 patients underwent echo and CMR (3±3 days); FAC (46±9 vs. 28±11), TAPSE (1.9±0.4 vs. 1.5±0.3) and S’ (11.4±2.3 vs. 10.0±2.6, all p≤ 0.001) were lower among RVdys patients, as were FS indices (RVOT 32±8 vs 17±10 | RVWD 40±11 vs 22±12 | RVLG 16±5 vs 9±4%; all p<0.001). FS indices yielded similar magnitude of correlation with CMR RVEF (r=0.73–0.56) as did FAC (r=0.70), which was slightly higher than TAPSE (r=0.47) and S’ (r=0.31; all p<0.001). FS indices decreased stepwise vs. CMR RVEF tertiles, as did FAC (all p<0.001). In multivariate analysis, FS in RVOT (regression coefficient 0.51 [CI 0.37–0.65]), RVWD (0.30 [0.19–0.41]), and RVLG (0.45 [0.20–0.71]; all p≤ 0.001) were independently associated with CMR RVEF. FS indices yielded good overall diagnostic performance (AUC: RVOT 0.89 [CI 0.82–0.97] | RVWD 0.87 [0.78–0.96] | RVLG 0.80 [0.70–0.90]; all p<0.001) for CMR-defined RVdy (RVEF<50%). Conclusions RV linear FS provides RV functional indices that parallel CMR RVEF. Parasternal long-axis RVOT width, 4-chamber RV width and length are independently associated with RVEF, supporting use of multiple FS indices for RV functional assessment.

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Traditional and innovative echocardiographic parameters for the analysis of right ventricular performance in comparison with cardiac magnetic resonance

Cited by 222 publications

References 19 publications

Contribution of Speckle Tracking to Estimation of Pulmonary Hypertension by Standard Doppler Echocardiography in Patients with Systemic Sclerosis and MCTD

Contribution of Speckle Tracking to Estimation of Pulmonary Hypertension by Standard Doppler Echocardiography in Patients with Systemic Sclerosis and MCTD

Current and future role of echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Echocardiographic linear fractional shortening for quantification of right ventricular systolic function—A cardiac magnetic resonance validation study

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