Background: Skilled delivery is encouraged as a single most important strategy in preventing maternal and neonatal morbidity and mortality. It ensures safe birth, reduce both actual and potential complications and increase the survival of most mothers and newborns. Little is known on current factors that affect utilization of skilled birth attendance in the study area. Therefore this study was aimed identify determinants of skilled birth attendance utilization among women who gave birth in the last 24 months preceding the studyMethods: A community based cross-sectional study was employed among women who gave birth in the last 24 months prior to the survey in Kembata Tembaro zone from April 1 to 30, 2020. 624 study participants were recruited for the study as eligible study participants. Multi-stage stratified sampling was used to select three districts and one town administrative unit of the study area. The data were collected and verified for their completeness, edited, and coded. Multivariate analysis was performed using the back ward LR method to identify factors independently associated with dependent variable. Statistical significance was declared at p-value of less than 0.05 and the strength of statistical association was measured by adjusted odds ratios and 95% confidence intervals.Results: In this study, 375(61.8%) women gave their last birth at health institutions being attended by skilled birth attendants. Place of residence [AOR (95% CI)=0.33(0.215, 0.582)], age at interview [AOR (95% CI=3.41(1.572, 5.449)], maternal education [AOR (95% CI)=1.50(1.336, 4.193)], history of still birth [AOR (95% CI)=3.85(2.144, 6.905)], maternal occupation [AOR (95% CI)=3.35(1.793,6.274)], husband occupation [AOR (95% CI)=2.69(1.701,7.986)], ANC visit [AOR (95% CI) =4.62(3.124, 7.324)], knowledge about obstetric complications [AOR (95% CI) =3.10(1.371,5.214)] and final decision maker about place of delivery [AOR (95% CI)= 3.64(1.701,7.986)] were significant with utilization of skill birth attendance.Conclusion: In this study, about two fifth of the respondents were delivering in the home without using unskilled delivery attendant. Place of residence, age at interview, maternal education, history of still birth, maternal occupation, husband occupation, ANC visit, knowledge about obstetric complications and final decision maker about place of delivery were determinants of utilization of skilled attendant delivery.