2008
DOI: 10.1016/j.jep.2008.07.034
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Traditional Chinese medicine for atopic eczema: PentaHerbs formula suppresses inflammatory mediators release from mast cells

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Cited by 77 publications
(47 citation statements)
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“…The large quantity of IgE antibodies generated by individuals during an allergic reaction to specific foods immediately bind to the FcRI receptors located on the surface of the mast cells in the gastrointestinal tract and other tissues. This provokes mast cell degranulation and subsequent release of active mediators, including histamine and specific cytokines, leading to hypersensitivity (Lorentz et al, 2000;Chan et al, 2008). Furthermore, serum IgG1 antibody also can cause mast cell degranulation and target organ injury by binding to FcRIII receptors located on the surface of the mast cells (Miyajima et al, 1997).…”
Section: Itemmentioning
confidence: 99%
“…The large quantity of IgE antibodies generated by individuals during an allergic reaction to specific foods immediately bind to the FcRI receptors located on the surface of the mast cells in the gastrointestinal tract and other tissues. This provokes mast cell degranulation and subsequent release of active mediators, including histamine and specific cytokines, leading to hypersensitivity (Lorentz et al, 2000;Chan et al, 2008). Furthermore, serum IgG1 antibody also can cause mast cell degranulation and target organ injury by binding to FcRIII receptors located on the surface of the mast cells (Miyajima et al, 1997).…”
Section: Itemmentioning
confidence: 99%
“…DC. (Compositae) in the proportion of 2:2:2:1:2 [27]. These herbs are anti-allergic, anti-inflammatory, anti-pruritic and sedative and have been extensively used in China for treatment of allergic diseases such as asthma and allergic rhinitis [28].…”
Section: Introductionmentioning
confidence: 99%
“…It helps to significantly improve the quality of life of patients. The clinically operational principle of PentaHerbs is as follows: (i) Flos Lonicerae and Herba Menthae clear damp-heat from the exterior; (ii) Cortex Moutan clears heat from blood; and (iii) Rhizoma Atractylodis and Cortex Phellodendri clear damp-heat from the interior [27].…”
Section: Introductionmentioning
confidence: 99%
“…They are also used in indigenous beverages in Korea and China (Wang, Clifford, & Sharp, 2008). Pharmacological studies have shown that extracts of the flower buds of L. japonica have a broad spectrum of biological activity, including antibacterial, anti-inflammatory, antinociceptive, antioxidant, antiangiogenic, antipyretic, antiviral, and hepatoprotective effects (Chan et al, 2008;Chang & Hsu, 1992;Choi, Jung, Kang, & Choi, 2007;Lee et al, 2001;Moon et al, 1999;Tang, Li, Chen, Guo, & Li, 2008;Xu, Oliverson, & Simmons, 2007;Yip, Chan, Pang, Tam, & Wong, 2006;Yoo, Kang, Song, Park, & Lim, 2008). A number of chemical constituents with diverse structures, including iridoids, flavonoids, saponins, polyphenols, and cerebrosides, have been isolated from this plant (Chang & Hsu, 1992;Chen, Wang, Ni, Chen, & Zhou, 2000;Choi et al, 2007;Kumar, Singh, Gupta, & Kaul, 2006;Lin et al, 2008;Lou, Tian, Yuan, & Ji, 1995;Peng, Mei, Jiang, Zhou, & Sun, 2000;Song et al, 2008;Teng, Wang, & Chen, 2000).…”
Section: Introductionmentioning
confidence: 99%