Traditional Chinese medicine for combating COVID-19

Chen, Kaixian; Chen, Hongzhuan

doi:10.1007/s11684-020-0802-9

Cited by 27 publications

(36 citation statements)

References 14 publications

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“…Although a great quantity of review articles have been published on the topic of TCM in COVID-19 13 , 14 , 19 , 23 , 25 , 35 , 71 , 87 , 168 , 171 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 248 , 249 , 250 , 251 , 252 , 253 , 254 , 255 , 256 , 257 , 258 , 259 , 260 , 261 , 262 , 263 , 264 , 265 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , our work offers something unique. 1) To our knowledge, this is the first review of TCM on COVID-19 that integrates evidence-based scientific findings from bedside to bench with the most comprehensive and updated literatures.…”

Section: Discussionmentioning

confidence: 99%

Traditional Chinese medicine in COVID-19

Lyu

Fan

Xiao

et al. 2021

Acta Pharmaceutica Sinica B

158

118

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COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the globe, posing an enormous threat to public health and safety. Traditional Chinese medicine (TCM), in combination with Western medicine (WM), has made important and lasting contributions in the battle against COVID-19. In this review, updated clinical effects and potential mechanisms of TCM, presented in newly recognized three distinct phases of the disease, are summarized and discussed. By integrating the available clinical and preclinical evidence, the efficacies and underlying mechanisms of TCM on COVID-19, including the highly recommended three Chinese patent medicines and three Chinese medicine formulas, are described in a panorama. We hope that this comprehensive review not only provides a reference for health care professionals and the public to recognize the significant contributions of TCM for COVID-19, but also serves as an evidence-based in-depth summary and analysis to facilitate understanding the true scientific value of TCM.

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Section: Discussionmentioning

confidence: 99%

Traditional Chinese medicine in COVID-19

Lyu

Fan

Xiao

et al. 2021

Acta Pharmaceutica Sinica B

158

118

View full text Add to dashboard Cite

show abstract

“…Although attention should be paid to the possible adverse effects of TCM, the benefits of TCM in the treatment of COVID-19 are also obvious ( Gray and Belessis, 2020 ; An et al, 2021 ; Ren et al, 2021 ). So far, the integration of TCM and Western medicine is effective for COVID based on previous pharmacological studies ( Chen and Chen, 2020 ; Ni et al, 2020 ; Xu and Zhang, 2020 ).…”

Section: Treatment Plan For Cardiovascular Complications Of Covid-19mentioning

confidence: 99%

Adverse Cardiovascular Effects of Anti-COVID-19 Drugs

et al. 2021

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection is the cause of the ongoing global pandemic. Mortality from COVID-19 infection is particularly high in patients with cardiovascular diseases. In addition, COVID-19 patients with preexisting cardiovascular comorbidities have a higher risk of death. Main cardiovascular complications of COVID-19 are myocardial infarction, myocarditis, acute myocardial injury, arrhythmias, heart failure, stroke, and venous thromboembolism. Therapeutic interventions in terms of drugs for COVID-19 have many cardiac adverse effects. Here, we review the relative therapeutic efficacy and adverse effects of anti-COVID-19 drugs.

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“…According to this analysis, the rules of TCM treatment were clarified, effective TCM formulas were established, and finally, “three formulas and three medicines” were determined [ 45 , 46 ]. By using big data analysis and artificial intelligence technology, the action mechanism of Qingfeipaidu decoction [ 47 – 49 ] was analysed, and a network molecular pharmacology study confirmed the active ingredients in this herbal formula, which laid a foundation for the development of related new drugs [ 46 , 50 , 51 ]. After pharmacological studies and first-line clinical trials in Wuhan, it was finally confirmed that this herbal formula could control the pulmonary inflammation of COVID-19 patients and inhibit the COVID-19 virus [ 48 ].…”

Section: Ai In Covid-19 Diagnosis and Treatmentmentioning

confidence: 99%

Application of Big Data and Artificial Intelligence in COVID-19 Prevention, Diagnosis, Treatment and Management Decisions in China

Dong

Zhou

et al. 2021

J Med Syst

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COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread rapidly and affected most of the world since its outbreak in Wuhan, China, which presents a major challenge to the emergency response mechanism for sudden public health events and epidemic prevention and control in all countries. In the face of the severe situation of epidemic prevention and control and the arduous task of social management, the tremendous power of science and technology in prevention and control has emerged. The new generation of information technology, represented by big data and artificial intelligence (AI) technology, has been widely used in the prevention, diagnosis, treatment and management of COVID-19 as an important basic support. Although the technology has developed, there are still challenges with respect to epidemic surveillance, accurate prevention and control, effective diagnosis and treatment, and timely judgement. The prevention and control of sudden infectious diseases usually depend on the control of infection sources, interruption of transmission channels and vaccine development. Big data and AI are effective technologies to identify the source of infection and have an irreplaceable role in distinguishing close contacts and suspicious populations. Advanced computational analysis is beneficial to accelerate the speed of vaccine research and development and to improve the quality of vaccines. AI provides support in automatically processing relevant data from medical images and clinical features, tests and examination findings; predicting disease progression and prognosis; and even recommending treatment plans and strategies. This paper reviews the application of big data and AI in the COVID-19 prevention, diagnosis, treatment and management decisions in China to explain how to apply big data and AI technology to address the common problems in the COVID-19 pandemic. Although the findings regarding the application of big data and AI technologies in sudden public health events lack validation of repeatability and universality, current studies in China have shown that the application of big data and AI is feasible in response to the COVID-19 pandemic. These studies concluded that the application of big data and AI technology can contribute to prevention, diagnosis, treatment and management decision making regarding sudden public health events in the future.

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Traditional Chinese medicine for combating COVID-19

Cited by 27 publications

References 14 publications

Traditional Chinese medicine in COVID-19

Traditional Chinese medicine in COVID-19

Adverse Cardiovascular Effects of Anti-COVID-19 Drugs

Application of Big Data and Artificial Intelligence in COVID-19 Prevention, Diagnosis, Treatment and Management Decisions in China

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