2022
DOI: 10.3389/fphar.2022.932739
|View full text |Cite
|
Sign up to set email alerts
|

Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research

Abstract: Podocytes form a key component of the glomerular filtration barrier. Damage to podocytes is referred to as “podocyte disease.” There are many causes of podocyte injury, including primary injury, secondary injury, and gene mutations. Primary podocytosis mostly manifests as nephrotic syndrome. At present, first-line treatment is based on glucocorticoid administration combined with immunosuppressive therapy, but some patients still progress to end-stage renal disease. In Asia, especially in China, traditional Chi… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2023
2023
2023
2023

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 175 publications
0
1
0
Order By: Relevance
“…Wei Zhang 1,2 , Anlan Hu 1,2 , Juan Wang 1,2 , Yudian Wang 1,2 , Xiaoyong Yu 2,* Along with the glomerular basement membrane (GBM) and endothelial cells, podocytes are important constituents of the glomerular filtration barrier, [4] and maintain homeostasis in the glomerular environment by interacting with endothelial cells. [5] When the body experiences oxidative and endoplasmic reticulum stress, podocyte structure and function are disrupted, the glomerular filtration barrier is unbalanced, and proteinuria and kidney tissue damage occur.…”
Section: Use Of Chinese Herbal Medicine To Inhibit Podocyte Damage As...mentioning
confidence: 99%
“…Wei Zhang 1,2 , Anlan Hu 1,2 , Juan Wang 1,2 , Yudian Wang 1,2 , Xiaoyong Yu 2,* Along with the glomerular basement membrane (GBM) and endothelial cells, podocytes are important constituents of the glomerular filtration barrier, [4] and maintain homeostasis in the glomerular environment by interacting with endothelial cells. [5] When the body experiences oxidative and endoplasmic reticulum stress, podocyte structure and function are disrupted, the glomerular filtration barrier is unbalanced, and proteinuria and kidney tissue damage occur.…”
Section: Use Of Chinese Herbal Medicine To Inhibit Podocyte Damage As...mentioning
confidence: 99%