Traditional Chinese Medicines Against COVID-19

Guo, Dean; Yao, Changliang; Wei, Wenlong; Bi, Qirui; Li, Jiayuan; Khan, Ikhlas A.; Bauer, Rudolf

doi:10.4103/2311-8571.353502

Cited by 17 publications

(7 citation statements)

References 197 publications

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“…In certain prior studies, it was noted that the combination of Chinese herbs may significantly lower the risks of intubation, ICU admission, and death in patients with mild to severe COVID-19 infections. 22,23 However, our findings did not yield sufficient evidence to support these observations. Additionally, there were no significant differences observed in the duration for nucleic acid test turning to negative and the risk of recurrent respiratory tract infections within three months between the two groups.…”

Section: Discussioncontrasting

confidence: 85%

The Efficacy and Safety of Shashen-Maidong Decoction Combined with Western Medicine in the Treatment of Omicron Infected Individuals Over 85 Years Old: A Retrospective Study

Lin,

Yin,

Zhang

et al. 2023

IDR

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Background During the Omicron variant outbreak of COVID-19 (2022–2023), Chinese healthcare institutions combined traditional Chinese medicine (TCM) with Western medical practices to treat COVID-19 patients, especially the elderly. The efficacy and safety of this approach, especially for individuals aged over 85, need further investigation. Methods In this retrospective study, a cohort of 62 patients aged over 85 years, diagnosed with COVID-19 infection, was examined. Among them, 34 patients were administered Shashen-Maidong decoction in conjunction with Western medicine (SMD+WM group), while the remaining 28 patients received only Western medicine (WM group). Comparative analysis was conducted between the two groups, encompassing parameters such as the duration for the nucleic acid test to turn negative, length of intensive care unit (ICU) stay, mortality rate, utilization of high-flow nasal cannula oxygen (HFNC), occurrence of endo-tracheal intubation, frequency of recurrent respiratory infections within three months, and various laboratory indicators. Results There were no significant differences observed between the two groups in terms of the duration for the nucleic acid test to turn negative, the length of ICU stay, mortality rate, utilization of HFNC, performance of endo-tracheal intubation, or the frequency of recurrent respiratory infections within three months (P > 0.05). However, in comparison to the WM group, the SMD+WM group exhibited notably lower growth rates in white blood cell (WBC) and neutrophil (NEUT) values. Additionally, the SMD+WM group demonstrated superior improvement in cardiac troponin I (cTnI) and B-type natriuretic peptide (BNP) values. Conclusion In contrast to the administration of Western medicine alone, the combined use of Shashen-Maidong decoction with Western medicine significantly suppresses the increase in WBC count, particularly in NEUT levels, in elderly patients diagnosed with COVID-19. Moreover, this combined treatment exhibits a protective effect on cardiac function and demonstrates a relatively safe profile.

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Section: Discussioncontrasting

confidence: 85%

The Efficacy and Safety of Shashen-Maidong Decoction Combined with Western Medicine in the Treatment of Omicron Infected Individuals Over 85 Years Old: A Retrospective Study

Lin,

Yin,

Zhang

et al. 2023

IDR

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“…The main reason may be that the research by Shoja et al [6] on the impact of COVID-19 on the workload of medical staff in Iran was during the early stage of the COVID-19 outbreak. Two years of anti-epidemic experience in China have led to a mature anti-epidemic strategy with regard to COVID-19, and nursing burden may be reduced as a result [25]. The results of multivariate analysis of support nurse workload in this study (Table 5), revealed that the 4 variables (presence of symptoms, support location, support job type, and total GHQ-12 score) explained the 14.4% variation in support nurse workload.…”

Section: Workload Status Of Support Nurses and Its Influencing Factorsmentioning

confidence: 63%

Factors influencing the mental health status of support nurses and their workload during the COVID-19 epidemic

Dai,

Xu,

Xue

et al. 2023

Int J Occup Med Environ Health.

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Objectives:The authors used the National Aeronautics and Space Administration Task Load Index (NASA-TLX) and general health questionnaire to analyze the factors influencing the mental health status and the workload of support nurses during the COVID-19 epidemic. Material and Methods:The authors conducted a cross-sectional survey of 349 support nurses in April-October 2022. Using QuestionStar, a powerful online survey tool, the authors administered surveys to the participants, collected data on the mental health status and workload of support nurses, and analyzed the influencing factors based on the collected data. Results: A total of 316 questionnaires were successfully collected, with an effective rate of 98.75%. The proportion of support nurses with mental health problems was 25% and the value of the NASA-TLX questionnaire was: M±SD 68.91±7.28 pts. Multi-factor analysis revealed that the number of children, family support, and nursing support location were the influencing factors of mental health status, while the multivariate analysis revealed that the presence of symptoms, nursing support location, support work type, and total 12-item General Health Questionnaire (GHQ-12) score were the influencing factors of the workload of support nurses. Conclusions: Compared to their counterparts in the plains, nurses working in isolated plateau regions who were caring for children and lacked family support, were more likely to have mental health issues. There was a positive correlation between the changes in GHQ-12 and NASA-TLX scores of the study participants. Compared to their counterparts in the plains and the tropical regions, nurses working in plateau regions had a heavier workload. As part of the follow-up measures to prevent and treat patients impacted by the COVID-19 epidemic, it is important to improve the mental health evaluation, consultation, and treatment of the support nurses to guarantee the high quality of the first-line support work.

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“…When individuals are exposed to an abundance of negative information, they become susceptible to perceiving higher levels of risk, leading to feelings of panic and anxiety. With an excessive amount of negative information received, a more intense sense of fear could be triggered [ 48 ] due to a reduced sense of control, which is at the core of anxiety generation and maintenance [ 49 ].…”

Section: Discussionmentioning

confidence: 99%

The effect of interpersonal relationship and epidemic attention on negative emotion among medical students: the mediating role of social satisfaction

Chen,

Huang,

Lin

2023

BMC Psychiatry

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Background Individuals are required to avoid close contact to reduce the probability of contracting the virus during the epidemics, which can lead to social isolation and exacerbate interpersonal relationship issues. Social satisfaction plays a crucial role in management in the period of pandemics and is strongly correlated with negative emotion. Medical students, as a special group of students, have a heavier burden of academic workload and greater pressure. They are also more likely to have access to epidemic information, which increases their susceptibility to negative emotions such as depression and anxiety. Therefore, it is necessary to investigate the impact and mechanisms among interpersonal, epidemic attention, social satisfaction, and negative emotions during the epidemics outbreak among medical students for improving the level of mental health in the post-epidemic era. Methods A total of 1,451 university students were included in this study. Self-administered questionnaires, including the Comprehensive Interpersonal Relationship Diagnostic Scale, the Self-Rating Anxiety Scale, and the Self-Rating Depression Scale, were utilized to construct structural equations to examine the mediating effects of social satisfaction. The study employed a multi-stage whole-group sampling approach for university students. Results Interpersonal relationships and epidemic attention positively predicted negative emotion levels. Interpersonal relationships negatively predicted social satisfaction, while epidemic attention positively predicted social satisfaction. Moreover, social satisfaction negatively predicted negative emotion levels. Notably, both interpersonal relationships and epidemic attention indirectly affected negative emotions through the mediating effect of social satisfaction. Conclusions Social satisfaction plays a mediating role in the effect of interpersonal relationships and epidemic attention on negative emotion. In the post-epidemic era, it is crucial to enhance support from family, school and society to improve social satisfaction of medical students. Immediate identification of negative emotions is essential, and targeted strategies should be developed to address mental health issues among medical students.

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Traditional Chinese Medicines Against COVID-19

Cited by 17 publications

References 197 publications

The Efficacy and Safety of Shashen-Maidong Decoction Combined with Western Medicine in the Treatment of Omicron Infected Individuals Over 85 Years Old: A Retrospective Study

The Efficacy and Safety of Shashen-Maidong Decoction Combined with Western Medicine in the Treatment of Omicron Infected Individuals Over 85 Years Old: A Retrospective Study

Factors influencing the mental health status of support nurses and their workload during the COVID-19 epidemic

The effect of interpersonal relationship and epidemic attention on negative emotion among medical students: the mediating role of social satisfaction

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