1. Human activities and development have contributed to declines in biodiversity across the globe. Understanding and addressing biodiversity loss will require the mobilization of diverse knowledge systems.2. While calls for interdisciplinary practices in environmental research date back decades, there has been a more recent push for weaving multiple knowledge systems in environmental research and management, specifically Indigenous knowledge systems (IKS) and Western sciences. 3. The use of multiple knowledge systems in environmental research can improve understanding of socio-ecological connections, build trust in research findings and help implement evidence-based action towards biodiversity conservation. Mobilizing multiple types of knowledge in environmental research and management can be beneficial; however, challenges remain.4. There is a need to understand how and where studies have woven IKS and Western sciences together in order to learn about frameworks and processes used, and identify best practices.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.