Traditional Herbal Remedies from Algeria for Treating Digestive Disorders

Boutlelis, Djahra Ali; Lmhanat, Iman; Benkaddour, Mounia; Benkherara, Salah; Laib, Ibtissam; Benine, Chaima

doi:10.22270/jddt.v13i1.5906

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…practice, yet in certain cultures, both men and women engage in this activity 13 . Consequently, fewer female respondents were interviewed during the present study compared to male respondents.…”

Section: Discussionmentioning

confidence: 99%

Therapeutic Potential of Traditional Medicinal Plants from Algeria for Treatment of Liver Diseases

Ali Boutlelis,

Sabrina,

Mounia

et al. 2023

Jordan j. pharm. sci.

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The objective of our study is to conduct an ethnobotanical investigation of traditional medicinal plants used by people in El-Oued state, southeast Algeria, for the treatment of liver diseases. We collected data through personal interviews and questionnaires. In total, we conducted interviews with 156 respondents, the majority of whom were aged 50 or older. Our study of medicinal plants used for treating liver diseases led to the discovery of 78 species from 41 families and various genera, including 52% of medicinal plants found in the wild. Approximately 77% of these plants were primarily used in dried form for remedy preparation. The most commonly employed preparation method was decoction. Interestingly, 70% of the participants mentioned Zizyphus lotus (L.) Lam., Silybum marianum L., and Atriplex halimus L. as sources for treating liver illnesses. This investigation revealed that many people in the research region still rely on herbal remedies to treat liver disorders. Moreover, the present study provides valuable ethnobotanical data on medicinal plants, serving as a foundational resource for future extensive research in this field.

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Section: Discussionmentioning

confidence: 99%

Therapeutic Potential of Traditional Medicinal Plants from Algeria for Treatment of Liver Diseases

Ali Boutlelis,

Sabrina,

Mounia

et al. 2023

Jordan j. pharm. sci.

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Therapeutic Efficacy of Helianthemum lippii Extract and Silver Nanoparticles Synthesized from the Extract against Cadmium-Induced Renal Nephrotoxicity in Wistar Rats

Laib,

Ali,

Alsalme

et al. 2024

Pharmaceuticals

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This study explored the therapeutic efficacy of Helianthemum lippii and silver nanoparticles (Ag NPs) synthesized using a H. lippii extract to alleviate cadmium-induced nephrotoxicity in Wistar rats. Sub-acute toxicity assessments of H. lippii (100 mg/kg, 1000 mg/kg, and 4000 mg/kg) and Ag NPs (2 mg/kg and 10 mg/kg) did not find any significant difference, compared with untreated control rats (n = 3 animals/group). Then, the adult Wistar rats were divided into one control (untreated/unexposed) and six experimental groups (n = 5/group): Ag NPs alone, H. lippii alone, exposure to 50 mg/kg CdCl2 in drinking water for 35 days, exposure to CdCl2 for 35 days followed by treatment with 0.1 mg/kg/day Ag NPs (intraperitoneal injection) and/or 100 mg/kg/day H. lippii by gavage for 15 days. In the CdCl2-exposed group, body weight decreased; urea, creatinine, and uric acid concentrations increased (p < 0.05 vs. control), indicative of nephrotoxicity, antioxidant defenses (SOD, GSH, and CAT) were reduced, and malondialdehyde concentration increased. Moreover, the kidney’s architecture in CdCl2-exposed rats was altered: fibrosis, inflammatory cell infiltration, glomerular destruction, and tubular dilatation. Treatment with H. lippii and/or Ag NPs after CdCl2 exposure improved some of the renal function and architecture alterations induced by CdCl2, and also increased body weight. This study underscores the potential therapeutic applications of H. lippii and Ag NPs to decrease oxidative stress and promote xenobiotic detoxification, in line with the growing emphasis on environmentally conscious practices in scientific research and healthcare.

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Traditional Herbal Remedies from Algeria for Treating Digestive Disorders

Cited by 2 publications

References 21 publications

Therapeutic Potential of Traditional Medicinal Plants from Algeria for Treatment of Liver Diseases

Therapeutic Potential of Traditional Medicinal Plants from Algeria for Treatment of Liver Diseases

Therapeutic Efficacy of Helianthemum lippii Extract and Silver Nanoparticles Synthesized from the Extract against Cadmium-Induced Renal Nephrotoxicity in Wistar Rats

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