Traditional Medicinal Plants of Sri Lanka and Their Derivatives of Benefit to the Nervous System

Perera, Pathirage Kamal; Meedeniya, Adrian Cuda Banda; Chamikara, Nupe Hewage Akila

doi:10.1007/978-981-33-4141-8_13

Cited by 4 publications

(4 citation statements)

References 140 publications

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“…The effects of medicinal plant preparations, their extracts, and isolated secondary metabolites on the central nervous system (CNS) have been extensively studied [120][121][122]. Numerous active principles from plants, such as polyphenols, polysaccharides, terpenoids, alkaloids, coumarins, tannins, and other natural bioactive ingredients, are used in the management of psychiatric and mental disorders [123][124][125].…”

Section: Pharmacognostic Investigations On the Cns Systemmentioning

confidence: 99%

Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine

Larit,

León

2023

Plants

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Ancient people sought out drugs in nature to prevent, cure, and treat their diseases, including mental illnesses. Plants were their primary source for meeting their healthcare needs. In Algeria, folk medicine remains a fundamental part of the local intangible knowledge. This study aims to conduct a comprehensive ethnomedicinal investigation and documentation of medicinal plants and the different plant formulations traditionally used in Algeria for the treatment of pain, psychiatric, and neurological disorders. It also intends to improve the current knowledge of Algerian folk medicine. Several scientific databases were used to accomplish this work. Based on this investigation, we identified 82 plant species belonging to 69 genera and spanning 38 distinct botanical families used as remedies to treat various psychological and neurological conditions. Their traditional uses and methods of preparation, along with their phytochemical composition, main bioactive constituents, and toxicity were noted. Therefore, this review provides a new resource of information on Algerian medicinal plants used in the treatment and management of neurological and psychological diseases, which can be useful not only for the documentation and conservation of traditional knowledge, but also for conducting future phytochemical and pharmacological studies.

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Section: Pharmacognostic Investigations On the Cns Systemmentioning

confidence: 99%

Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine

Larit,

León

2023

Plants

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“…Curcumin's protective effects on myocardial [21] One of the main mediators of inflammation is TNF. However, it wasn't until our team isolated two distinct molecules from macrophages and lymphocytes that we were able to determine the exact chemical composition of TNF, there is a study showing Suppression of TNF by curcumin in vivo that curcumin can suppress TNF-induced NF-κB activation and the expression of pro-inflammatory genes Since then, numerous mechanisms by which curcumin can exhibit anti-inflammatory activity have been proposed [22].…”

Section: Conclusion and Recommendationsmentioning

confidence: 99%

The Role of curcumin extract in Ameliorating Cyclophosphamide-Induced Cardiotoxicity

Thanoon Al-Bayati,

Jaffat

2023

BIO Web Conf.

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Cyclophosphamide, a chemotherapeutic and immunosuppressive drug, has been linked to problems after bone marrow transplantation in the past. More recently, it has been demonstrated that cardiotoxicity limits the dose of cyclophosphamide, and cardiology is receiving more attention. Though the exact mechanism of cyclophosphamide-induced cardiotoxicity is unknown, oxidative and nitrative stress are suspected to play a role. As a result, the focus of this review is on antioxidants and how they can reduce or prevent cyclophosphamide-induced cardiotoxicity. It will place a special emphasis on the cardioprotective properties of naturally occurring, plant-derived antioxidants such as curcumin extract, which have recently attracted a lot of interest.

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“…Plant regeneration, particularly through shoot morphogenesis, occasionally results in genetically variable and chimeric plants. However, in the case of somatic embryogenesis, the plants are genetically similar whether the somatic embryos are directly or indirectly produced [ 89 ]. Reports suggested that auxin (2,4-dichlorophenoxyacetic acid, indole acetic acid) acts as a trigger molecule for the induction of somatic embryogenesis.…”

Section: Micropropagationmentioning

confidence: 99%

Biotechnological Intervention and Secondary Metabolite Production in Centella asiatica L.

Ganie

Ahmad

Shahzad

et al. 2022

Plants

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Centella asiatica L., commonly known as Gotu kola, Indian pennywort, and Asiatic pennyworts, is an herbaceous perennial plant that belongs to the family Apiaceae and has long been used in the traditional medicine system. The plant is known to produce a wide range of active metabolites such as triterpenoids including asiatic acid, asiaticoside, brahmoside, and madecassic acid along with other constituents including centellose, centelloside, and madecassoside, etc., which show immense pharmacological activity. Due to its beneficial role in neuroprotection activity, the plant has been considered as a brain tonic. However, limited cultivation, poor seed viability with low germination rate, and overexploitation for decades have led to severe depletion and threatened its wild stocks. The present review aimed to provide up-to-date information on biotechnological tools applied to this endangered medicinal plant for its in vitro propagation, direct or indirect regeneration, synthetic seed production, strategies for secondary metabolite productions including different elicitors. In addition, a proposed mechanism for the biosynthesis of triterpenoids is also discussed.

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Traditional Medicinal Plants of Sri Lanka and Their Derivatives of Benefit to the Nervous System

Cited by 4 publications

References 140 publications

Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine

Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine

The Role of curcumin extract in Ameliorating Cyclophosphamide-Induced Cardiotoxicity

Biotechnological Intervention and Secondary Metabolite Production in Centella asiatica L.

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