Traditional Thai exercise (Ruesi Dadton) for improving motor and cognitive functions in mild cognitive impairment: a randomized controlled trial

Abstract

This study determined the effectiveness of a 12-week cycle of Ruesi Dadton (RSD) among older adults with mild cognitive impairment (MCI), for improving cognitive and physical performance. Seventy-six participants were included and were divided equally into two groups. A group performed RSD exercise for 60 min, 3 times/wk for 12 weeks, and the control group did not perform RSD exercise. The primary endpoint was cognitive function, as assessed by the Montreal cognitive assessment (MoCA), Mini-Mental State Examination, verbal fluency (VF) test, and trail making test parts A and B (TMT-A and TMT-B). The secondary endpoints were the Timed Up and Go (TUG) test, handgrip, and gait speed results, which were used to evaluate the physical function. There were significant differences in the TMT-B and handgrip scores (P< 0.05) between the two groups. Both groups had improved MoCA scores (P< 0.05) and normal walking speeds (P< 0.01). Additionally, the RSD group showed improved VF test (P< 0.01), TMT-B (P< 0.01), and TUG test (P< 0.05); a negative correlation was found between MoCA and TUG test (P< 0.05). However, high walking speed and handgrip (P< 0.05) worsened in the control group. RSD exercise resulted in relevant improvements in the cognitive and physical functions in MCI.

The influence of exercise interventions on cognitive functions in patients with amnestic mild cognitive impairment: A systematic review and meta-analysis

“…Two studies (20%) were performed in Japan ( 41 , 42 ). Two studies (20%) were conducted in Korea ( 18 , 43 ) and three studies (30%) were performed in Thailand ( 44 – 46 ).…”

“…Two studies (20%) were performed in Japan (41,42). Two studies (20%) were conducted in Korea (18,43) and three studies (30%) were performed in Thailand (44)(45)(46). Additionally, the quality of included studies was evaluated according to the guidelines established by Higgins (34).…”

Immediate effects of multimodal cognitive therapy in mild cognitive impairment

“…A previous study showed that light therapy (1000 or 300 lx) improved depression (22%), sleep efficiency (4%), and cognitive function (12%) in older adults with dementia (Riemersma- Van Der Lek et al, 2008). Khanthong et al (2021) reported that Thai exercises, including deep breathing and holding, improved cognitive function (9%) in 71 older adults with MCI (Khanthong et al, 2021).…”

“…Calabrò et al (2015) reported that RAGT, in addition to cognitive training, had positive effects on cognitive function with an improvement of 29% in the Mini-Mental State Examination (MMSE) (Calabrò et al, 2015). A previous meta-analysis reported that CCT improved (Khanthong et al, 2021;Riemersma-Van Der Lek et al, 2008) cognitive functions related to memory and executive function in older adults with MCI (Zhang et al, 2019). Han et al (2020) demonstrated that cognitive intervention with musical stimuli improved memory (37%), attention (9%), and orientation (8%), and depression (8%) in 24 patients with MCI compared to the controls who received no intervention (Han et al, 2020).…”

Does Gotu kola supplementation improve cognitive function, inflammation, and oxidative stress more than multicomponent exercise alone? – a randomized controlled study

“…Exercise has become an increasingly important non-pharmacological therapy in preventing cognitive function decline in patients with cognitive impairment (Huang et al, 2022). According to these findings, randomized controlled trials investigating the efficacy of exercise in subjects with MCI showed some positive cognitive outcomes, mainly on global cognition, executive function, or attention (Baker et al, 2010;Khanthong et al, 2021;Lam et al, 2011;Loprinzi et al, 2019;Nagamatsu et al, 2012;Nagamatsu et al, 2013;Suzuki et al, 2013;Varela et al, 2012). In addition, recent systematic review and meta-analysis studies have also discovered that multicomponent exercise is most likely to protect the global cognition and executive function of MCI patients (Huang et al, 2022;Wang et al, 2020).…”