Traditional usage, phytochemistry and pharmacology of the South African medicinal plant Boophone disticha (L.f.) Herb. (Amaryllidaceae)

Nair, Jerald J.; Staden, J. Van

doi:10.1016/j.jep.2013.10.053

Cited by 50 publications

(31 citation statements)

References 108 publications

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“…Today, scientists have revealed that plants contain constituents that can work in synergy to effect certain properties of Arrow poison by the Bushmen. 6 Mental diseases, 13,16,17 Early mental disease, 13 emetic, antimalarial, antimicrobial, anti-inflammatory, and analgesic properties. 26,27 Intestinal ulcers, indigestion, heartburn, and cleans kidneys and bladder, 6,23,25 antiseptic properties.…”

Section: Diversity Of Medicinal Plants Usedmentioning

confidence: 99%

Ethnobotanical Survey of Medicinal Plants Used to Treat Mental Illnesses in the Berea, Leribe, and Maseru Districts of Lesotho

Mabaleha

Zietsman

Wilhelm

et al. 2019

Natural Product Communications

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Mental illnesses (MIs) such as anxiety, epilepsy, major depression, schizophrenia, sleep disorder, and pain influence the quality of life severely. According to the World Health Organization Atlas for Mental Health (2014), the formal health sector in Lesotho has only 13.7 mental health workers per 100 000 of the population, which breaks down to 0.1 psychiatrist and other medical doctors, 0.3 psychologists, 4.7 nurses, and 5.2 social workers. Traditional health practitioners (THPs) have always played a significant role in the prevention and treatment of MIs, via utilization of Lesotho’s vast diversity of plants. This investigation aims to determine which medicinal plants are used for the treatment of MIs in the Berea, Leribe, and Maseru districts of Lesotho. A combination of unstructured and semistructured one-on-one interviews were conducted with 27 THPs. They were interviewed about the status of MIs in Lesotho, diagnostic methods, medicinal plants used, and preparation and administration of the herbal remedies in the treatment of MIs. A total of 43 different plant species (indigenous and exotic) were indicated by the THPs as commonly used to treat neurological disorders. With the exception of one unidentified plant, the plants represented 26 families and 42 genera. The most common families are the Asteraceae (9 species), Fabaceae (5 species), and Rosaceae (3 species). The most cited plant species were Morella serrata (Myricaceae) (26%), followed by Xysmalobium undulatum (Asclepiadaceae) (22%), and Afroaster hispidus (Asteraceae) (15%). This survey provides, for the first time, a database of Lesotho’s medicinal plants that are used to treat MIs.

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Section: Diversity Of Medicinal Plants Usedmentioning

confidence: 99%

Ethnobotanical Survey of Medicinal Plants Used to Treat Mental Illnesses in the Berea, Leribe, and Maseru Districts of Lesotho

Mabaleha

Zietsman

Wilhelm

et al. 2019

Natural Product Communications

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“…The genus Narcissus L. is a member of monocotyledonous family Amaryllidaceae, which is well known in horticulture for its ornamental plants and in medicine for the content of biologically active secondary metabolites called Amaryllidaceae alkaloids [1]. These compounds which have numerous bioactivities including analgesic, antiviral, antibacterial, antifungal, antimalarial, antitumor and cytotoxic activities have been increasingly important to the researchers [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous quantitative analysis of biologically important Amaryllidaceae alkaloids in Narcissus tazetta L. subsp. tazetta by HPLC/PDA

Karakoyun¹,

Unver-Somer²

2019

jrp

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The present study was conducted for the quantitative determination of biologically active Amaryllidaceae alkaloids, galanthamine and lycorine, in the bulbs and aerial parts of a subspecies naturally growing in Turkey namely, Narcissus tazetta L. subsp. tazetta collected from Muğla/Turkey. A reverse phase high performance liquid chromatographic method using an isocratic system consisting of trifluoroacetic acid:water:acetonitrile (0.01:90:10) with a flow rate of 1 mL/min was carried out. Photodiode array detection was employed to determine the UV-visible spectral characteristics of the alkaloids. Determination of acetylcholinesterase and butyrylcholinesterase inhibitory activities of different parts of mentioned subspecies were accomplished using a microplate assay modified from Ellman's method. This is the first report of the galanthamine content of Narcissus tazetta subsp. tazetta of Turkish origin. 0.0051% and 0.0055% galanthamine was detected in the bulbs and aerial parts of the plant, respectively. Also, lycorine was determined as 0.0250% in the bulbs and 0.0672 % in the aerial parts.

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“…The Amaryllidaceae is known for their alkaloid compounds, of which many have been identified with anti-viral activity. The major group of secondary metabolites occurring in the Amaryllidaceae is isoquinoline alkaloids with various structural variations (Nair and Van Staden, 2014). Lycorine, narciclasine and pretazettine are well known compounds isolated from this family.…”

Section: Anti-hiv Activity Of Medicinal Plant Compoundsmentioning

confidence: 99%

Anti-HIV activity of southern African plants: Current developments, phytochemistry and future research

Prinsloo

Marokane

Street

2018

Journal of Ethnopharmacology

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An investigation of the plants from southern Africa with ethnobotanical use for the treatment of HIV, management of HIV or HIV-related symptoms, therefore provide a very good analysis of the major assays employed and the anti-viral compounds and compound groups identified. The similarity in identified anti-viral compounds worldwide should support the progression from in vitro studies to in vivo testing in development of affordable and effective anti-HIV agents for countries with high infection and mortality rates due to HIV/AIDS.

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Traditional usage, phytochemistry and pharmacology of the South African medicinal plant Boophone disticha (L.f.) Herb. (Amaryllidaceae)

Cited by 50 publications

References 108 publications

Ethnobotanical Survey of Medicinal Plants Used to Treat Mental Illnesses in the Berea, Leribe, and Maseru Districts of Lesotho

Ethnobotanical Survey of Medicinal Plants Used to Treat Mental Illnesses in the Berea, Leribe, and Maseru Districts of Lesotho

Simultaneous quantitative analysis of biologically important Amaryllidaceae alkaloids in Narcissus tazetta L. subsp. tazetta by HPLC/PDA

Anti-HIV activity of southern African plants: Current developments, phytochemistry and future research

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