Traditional uses, chemical composition and pharmacological activities of Alstonia R. Br. (Apocynaceae): A review

Chemical Profile and Biological Potential of Scaptotrigona Bee Products (Hymenoptera, Apidae, Meliponini): An Review

“…From this perspective, verification of the antibacterial activity of natural products has become the target of studies aimed at discovering substances with the potential to reduce or reverse these resistance mechanisms. [73] In the study carried out by Nishio et al [74] the antibacterial activity of honey produced by Scaptotrigona bipunctata and S. postica bees was tested using the minimum inhibitory concentration (MIC) against strains of gram-positive and gram-negative bacteria, including multidrug-resistant strains, including Enterococcus faecalis, Enterococcus faecium, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica subsp. enterica serovar Enteritidis, S. enterica subsp.…”

Polycyclic pyrroloindoline-containing natural products with a unique 3-heptyl-2a,4a-diazapentaleno[1,6-ab]indene core isolated from Alstonia scholaris

“…10 So far, nearly 135 compounds have been reported in this species and most of them are monoterpene indole alkaloids (MIAs). 11 Compared to the extensive investigation of MIAs, only fourteen PiNPs, namely echitamine, 12 N b -demethylechitamine, 12 17- O -acetylechitamine, 12 echitaminic acid, 13 3- epi -dihydrocorymine, 14 3- epi -dihydrocorymine 3-acetate, 14 3- epi -dihydrocorymine 17-acetate, 14 leuconoxine, 15 scholarisine G, 16 scholarisin VI, 17 alistonitrine A, 18 alstobrogaline, 19 scholarinine A, 20 and alstoscholarinine E, 21 were isolated from this species, and can be classified into five PiNP carbon skeletons.…”