Traditional uses, chemical diversity and biological activities of Panax L. (Araliaceae): A review

Liu, Lu; Xu, Furong; Wang, Yuanzhong

doi:10.1016/j.jep.2020.112792

Cited by 76 publications

(42 citation statements)

References 205 publications

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“…Traditionally, ginger and ginger volatile oils, curcumin, Panax L. ( Araliaceae ) and garlic are recommended and used to strengthen immunity and reduce the likelihood of inflammatory respiratory diseases [ 2 , 17 , 18 ]. In an in vitro study [ 19 ], Allium sativum L. ( Amaryllidaceae ) extract inhibited influenza A (H 1 N 1 ) virus by inhibiting the synthesis of viral nucleoproteins and polymerase activity.…”

Section: Resultsmentioning

confidence: 99%

Medicinal Plants to Strengthen Immunity during a Pandemic

et al. 2020

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The development of new effective anti-coronavirus drugs and therapies is important, but it requires significant human, financial and, most importantly, time expenditures. The current pandemic is neither the first nor the last. Humanity has already accumulated considerable survival experience. We cannot do without prevention and epidemiological protection measures. This study reviews medicinal plants that grow in Northeast Asia and whose antioxidant, antiviral, anti-inflammatory and immunomodulatory characteristics are already known, also in the framework of the prevention and treatment of pneumonia of various etiologies. The need for a comprehensive approach to maintaining immunodefences, including functional foods and positive emotions, is emphasized. In the period of pandemics, it is important to research various areas that allow to us accumulate a critical mass of information and cope with the next global disease.

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Section: Resultsmentioning

confidence: 99%

Medicinal Plants to Strengthen Immunity during a Pandemic

et al. 2020

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“…A variety of pharmacological effects are attributed to ginseng. For example, it is used to improve intelligence, to treat impotence, to treat hemorrhage, to relax, and to slow aging [ 218 ]. American ginseng medical use is more recent and has gained popularity in Western countries over recent decades.…”

Section: Discussionmentioning

confidence: 99%

“…The fresh root of ginseng can be directly chewed after peeling or soaked in wine for drinking and chewing. In China and Korea, it is boiled with chicken to prepare energy drinks, teas, and candies [ 218 ].…”

Section: Discussionmentioning

confidence: 99%

Pharmacology of Herbal Sexual Enhancers: A Review of Psychiatric and Neurological Adverse Effects

et al. 2020

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Sexual enhancers increase sexual potency, sexual pleasure, or libido. Substances increasing libido alter the concentrations of specific neurotransmitters or sex hormones in the central nervous system. Interestingly, the same pathways are involved in the mechanisms underlying many psychiatric and neurological disorders, and adverse reactions associated with the use of aphrodisiacs are strongly expected. However, sexual enhancers of plant origin have gained popularity over recent years, as natural substances are often regarded as a safer alternative to modern medications and are easily acquired without prescription. We reviewed the psychiatric and neurological adverse effects associated with the consumption of herbal aphrodisiacs Areca catechu L., Argemone Mexicana L., Citrus aurantium L., Eurycoma longifolia Jack., Lepidium meyenii Walp., Mitragyna speciosa Korth., Panax ginseng C. A. Mey, Panax quinquefolius L., Pausinystalia johimbe (K. Schum.) Pierre ex Beille, Piper methysticum G. Forst., Ptychopetalum olacoides Benth., Sceletium tortuosum (L.) N. E. Brown, Turnera diffusa Willd. ex. Schult., Voacanga africana Stapf ex Scott-Elliot, and Withania somnifera (L.) Dunal. A literature search was conducted on the PubMed, Scopus, and Web of Science databases with the aim of identifying all the relevant articles published on the issue up to June 2020. Most of the selected sexual enhancers appeared to be safe at therapeutic doses, although mild to severe adverse effects may occur in cases of overdosing or self-medication with unstandardized products. Drug interactions are more concerning, considering that herbal aphrodisiacs are likely used together with other plant extracts and/or pharmaceuticals. However, few data are available on the side effects of several plants included in this review, and more clinical studies with controlled administrations should be conducted to address this issue.

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“…The chemical composition of the Panax genus can be classified into four main groups: saponins, polyacetylenes, polysaccharides, and flavonoids. 6,7 Besides, there are eight other sub-groups, including phenolics, sterols, carbohydrates, proteins, amino acids, minerals, lipids, and fatty acids. 7,8 Several plants of the Panax species have long been used as medicinal herbs in oriental countries, for example, P. ginseng C.A.…”

Section: Introductionmentioning

confidence: 99%

Panabipinoside A and panabipinoside B, two new oleanane triterpenoid saponins from the roots of Panax bipinnatifidus with nitric oxide inhibitory activity

Kiệm

Hoàng

Anh

et al. 2021

Journal of Chemical Research

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Panax bipinnatifidus belongs to the ginseng genus and it is used in traditional Vietnamese and Chinese medicine. Phytochemical studies of the roots of this plant led to the isolation of two new oleanane triterpenoid saponins, panabipinoside A and panabipinoside B, and three known compounds, ginsennoside Ro, 3- O- β-D-glucopyranosyl-(1→3)- β-glucuronopyranosyl oleanolic acid, and spinasaponin A 28- O-glucoside. Their structures are established by extensive spectroscopic analysis (IR, high-resolution electrospray ionization mass spectrometry, and nuclear magnetic resonance) and by comparison of the spectral data with those reported in the literature. The anti-inflammatory activity of the isolated compounds is evaluated by their inhibition of nitric oxide production in lipopolysaccharide stimulated RAW 264.7 cells. Compounds 2–5 showed inhibitory effects on nitric oxide production with IC50 values of 0.62 ± 0.09, 0.21 ± 0.04, 0.30 ± 0.03, and 0.45 ± 0.05 µg/mL, respectively, compared to value of 8.08 ± 0.09 µg/mL for the positive control compound, NG-monomethyl-L-arginine.

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Traditional uses, chemical diversity and biological activities of Panax L. (Araliaceae): A review

Cited by 76 publications

References 205 publications

Medicinal Plants to Strengthen Immunity during a Pandemic

Medicinal Plants to Strengthen Immunity during a Pandemic

Pharmacology of Herbal Sexual Enhancers: A Review of Psychiatric and Neurological Adverse Effects

Panabipinoside A and panabipinoside B, two new oleanane triterpenoid saponins from the roots of Panax bipinnatifidus with nitric oxide inhibitory activity

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