Traditional uses, phytochemistry, pharmacology, processing methods and quality control of Lindera aggregata (Sims) Kosterm: A critical review

Tao, Yi; Deng, Yuling; Wang, Ping

doi:10.1016/j.jep.2023.116954

Cited by 6 publications

(4 citation statements)

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“…The genus Lindera is one of the most core genera, with approximately 100 species distributed in tropical, subtropical and temperate regions of Asia and the Midwest of the USA [ 3 ]. In China, there are more than 40 species, accounting for 46% of the total genus [ 4 ]. Most of the plants of the genus Lindera have a special smell and can be used for cooking and medical purposes [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…In China, there are more than 40 species, accounting for 46% of the total genus [ 4 ]. Most of the plants of the genus Lindera have a special smell and can be used for cooking and medical purposes [ 4 , 5 ]. Among them, L. aggregata is a kind of plant with great medicinal value in this genus, which was widely used in the traditional medicine industry as early as 2000 years ago.…”

Section: Introductionmentioning

confidence: 99%

“…Among them, the L. aggregata produced in Zhejiang Tiantai is of the best quality, which is also known as “Tiantai Wu-Yao”. It is the authentic origin of L. aggregata since the Song Dynasty [ 4 ]. Furthermore, L. aggregata contains a large number of isoquinoline alkaloids [ 7 ], flavonoids [ 8 ], sesquiterpene lactones [ 9 ] and polyphenols [ 10 ], with anti-cancer, anti-inflammatory, antibacterial, antioxidant and other activities [ 6 , 11 , 12 , 13 ], that can be used to treat chest pain, abdominal pain, inflammation, frequent urination, dysmenorrhea, rheumatic diseases and other diseases [ 6 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…Up to now, the research on L. aggregata is mainly focused on its chemical composition and pharmacological action [ 4 , 5 ], but there are few studies on its genetic diversity, evolution and phylogeny. Although the chloroplast genome of L. aggregata has been reported, the samples collected are mainly from Zhejiang Hangzhou or Yunnan [ 20 , 27 ], and the trueborn origin region (Zhejiang Tiantai) has not been reported, and the previous research content is also only a simple characteristic description.…”

Section: Introductionmentioning

confidence: 99%

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Comparative Analysis of Chloroplast Genomes of “Tiantai Wu-Yao” (Lindera aggregata) and Taxa of the Same Genus and Different Genera

Shi,

Chen,

Jiang

et al. 2024

Genes

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Lindera aggregata is a species of the Lauraceae family, which has important medicinal, economic and ornamental values. In this study, we sequenced, assembled and annotated the chloroplast genome of L. aggregata and reannotated and corrected eight unverified annotations in the same genus. The chloroplast genomes taxa from Lindera and from different genera of Lauraceae were compared and analyzed, and their phylogenetic relationship and divergence time were speculated. All the 36 chloroplast genomes had typical quadripartite structures that ranged from 150,749 to 154,736 bp in total length. These genomes encoded 111–112 unique genes, including 78–79 protein-coding genes, 29–30 tRNA and 4 rRNA. Furthermore, there were 78–97 SSRs loci in these genomes, in which mononucleotide repeats were the most abundant; there were 24–49 interspersed repeats, and forward repeat types were the most frequent. The codon bias patterns of all species tended to use codons ending with A or U. Five and six highly variable regions were identified within genus and between genera, respectively, and three common regions (ycf1, ndhF-rpl32 and rpl32-trnL) were identified, which can be used as important DNA markers for phylogeny and species identification. According to the evaluation of the Ka/Ks ratio, most of the genes were under purifying selection, and only 10 genes were under positive selection. Finally, through the construction of the evolutionary tree of 39 chloroplast genomes, the phylogenetic relationship of Lauraceae was clarified and the evolutionary relationship of Lindera was revealed. The species of genus Lindera experienced rapid adaptive radiation from Miocene to Pleistocene. The results provided valuable insights for the study of chloroplast genomes in the Lauraceae family, especially in the genus Lindera.

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Section: Introductionmentioning

confidence: 99%